Results 21 to 30 of about 63,661 (296)

Sex assignment in conditions affecting sex development [PDF]

, 2017
The newborn infant with atypical genitalia presents a challenging clinical scenario and requires expert input. There have been appreciable advances in our knowledge of the underlying causes that may lead to a mere difference or a more serious disorder of
Ahmed, S. Faisal, Markosyan, Renata
core   +1 more source

Expression profile of the SOX9 gene in the testes of sexually immature and mature male goats (Capra hircus), and its potential influence on postnatal testis development

Veterinární Medicína, 2017
The aim of this study was to compare the expression levels of the SOX9 (SRY-box 9) gene in the testes of 18 White improved male goats (Capra hircus) divided into three age groups (one, 10 and 15 months of age with seven, eight and three individuals per ...
I. Szatkowska, M. Jedrzejczak-Silicka, A. Dybus, B. Wiszniewska, J. Udala, D. Zaborski, J. Wojcik, T. Stankiewicz, W.S. Proskura   +8 more
doaj   +1 more source

The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation. [PDF]

, 2016
Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated.
Chang, Hong-Tai, Chang, Yu-Chang, Chen, Chi-Long, Ger, Luo-Ping, Hsiao, Michael, Huang, Ming-Shyan, Jan, Yi-Hua, Lai, Tsung-Ching, Lin, Tsung-Chieh, Lin, Yuan-Feng, Liu, Yu-Peng, Pan, Wen-An, Shyy, John Y-J, Su, Chia-Yi, Tsai, Ming-Daw, Wu, Pei-Yu, Yang, Chih-Jen, Yeh, Chi-Tai   +17 more
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DETECTION OF SRY OF NEWBORN RABBITS MENT FOR XENOIMPLANTATES

Scientific Papers Animal Science and Biotechnologies, 2023
The aim of this study was sex-detection of nexborn rabbits with molecular-genetics analyses of SRY (specific region of Y chromosome) sequence. This region is present only in male animals, in females is missing.
ALICA RAFAYOVÁ, ANNA TRAKOVICKÁ, V. PARKÁNYI, A. KOVÁČIK   +3 more
doaj  

Prevalence of SRY and DAX-1 gene deletion in patients with Cryptorchidism and Hypospadias – A Pilot study in North Indian Children

Asian Journal of Medical Sciences, 2015
Background: Cryptorchidism and hypospadias are common problems in males attending the pediatric surgery clinic. These two abnormalities are also associated with genetic syndromes/disorders of sexual development (DSD).
Krishna Mohan Gulla
doaj   +1 more source

NHERF2/SIP-1 Interacts with Mouse SRY via a Different Mechanism than Human SRY [PDF]

Journal of Biological Chemistry, 2005
In mammals, male sex determination is controlled by the SRY protein, which drives differentiation of the bipotential embryonic gonads into testes by activating the Sertoli cell differentiation program. The morphological effects of SRY are well documented; however, its molecular mechanism of action remains unknown.
Thevenet, L., Albrecht, Kh, Malki, S., Berta, P., Boizet-Bouhoure, B., Poulat, F.   +5 more
openaire   +2 more sources

Mutations in the testis-specific enhancer of SOX9 in the SRY independent sex-determining mechanism in the genus Tokudaia. [PDF]

PLoS ONE, 2014
SRY (sex-determining region Y) is widely conserved in eutherian mammals as a sex-determining gene located on the Y chromosome. SRY proteins bind to the testis-specific enhancer of SOX9 (TES) with SF1 to upregulate SOX9 expression in undifferentiated ...
Ryutaro Kimura, Chie Murata, Yoko Kuroki, Asato Kuroiwa   +3 more
doaj   +1 more source

A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development [PDF]

, 2011
Disorders of sex development (DSD) are congenital conditions where chromosomal, gonad or genital development is atypical. In a significant proportion of 46,XY DSD cases it is not possible to identify a causative mutation, making genetic counseling ...
AJ Notini, AJ Paige, AK Bednarek, Andrew Sinclair, D Wilhelm, DM Maatouk, E Sutton, Erin Turbitt, H Stoop, Jacqueline Hewitt, JH Ludes-Meyers, Leendert Looijenga, LH Looijenga, M Cools, M Cools, Martine Cools, MI Nunez, N Bouteille, PA Lee, Peter Koopman, R Hersmus, Remko Hersmus, RI Aqeilan, RI Aqeilan, RI Aqeilan, RI Aqeilan, S Del Mare, SJ White, SJ White, Stefan White, Stenvert Drop, Vincent Harley, Yvonne van der Zwan   +32 more
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The evolutionary process of mammalian sex determination genes focusing on marsupial SRYs

BMC Evolutionary Biology, 2018
Background Maleness in mammals is genetically determined by the Y chromosome. On the Y chromosome SRY is known as the mammalian male-determining gene. Both placental mammals (Eutheria) and marsupial mammals (Metatheria) have SRY genes.
Yukako Katsura, Hiroko X. Kondo, Janelle Ryan, Vincent Harley, Yoko Satta   +4 more
doaj   +1 more source

A family case of fertile human 45,X,psu dic(15;Y) males [PDF]

, 2006
We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal
Andersson M, Baumstark A, Buonadonna AL, C.S. Nagarajappa, Callen DF, Charchar FJ, Fracarro M, Freije D, Gal A, Haaf T, Hsu TC, I. Hansmann, I. Palaniappan, Koiffmann CP, Ma NS, Maserati E, Matthey R, N. Chandra, P.M. Gopinath, R. Wimmer, Ried T, Schempp W, Schiebel K, Schmid M, Siffroi JP, Subrt I, Tiemeier DC, W. Schempp, Weber B, White LM   +29 more
core   +1 more source