Results 41 to 50 of about 63,661 (296)

Global genome analysis of the downstream binding targets of testis determining factor SRY and SOX9. [PDF]

PLoS ONE, 2012
A major event in mammalian male sex determination is the induction of the testis determining factor Sry and its downstream gene Sox9. The current study provides one of the first genome wide analyses of the downstream gene binding targets for SRY and SOX9
Ramji K Bhandari, Md M Haque, Michael K Skinner   +2 more
doaj   +1 more source

The Sex-Determining Factors SRY and SOX9 Regulate Similar Target Genes and Promote Testis Cord Formation during Testicular Differentiation

Cell Reports, 2014
Male sex determination is mediated sequentially by sex-determining region Y (SRY) and related SRY-box 9 (SOX9) transcription factors. To understand the gene regulatory hierarchy for SRY and SOX9, a series of chromatin immunoprecipitation and whole-genome
Yunmin Li, Ming Zheng, Yun-Fai Chris Lau   +2 more
doaj   +1 more source

Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]

, 2009
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H., Baker, P.J., Huhtaniemi, I., Morris, I.D., O'Shaughnessy, P.J.   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Early Diagnosis of Fetal Sex and its Relationship to Some Biochemical and Physiological Variables in Pregnant Women in Salah Al-Din Governorate

Proceedings of the International Conference on Applied Innovations in IT
Genes for sex determination are widely analyzed and used to predict fetal sex during different trimesters of pregnancy. However, their correlation with sex prediction based on ultrasound results, as well as with testosterone and estrogen levels in the ...
Noor Lateef Omer, Hussien Mohammad Tayawi   +1 more
doaj   +1 more source

Sex determination [PDF]

, 2012
Multicellular animals are a diverse lot, with widely varied body plans and lifestyles. One feature they share, however, is a nearly universal reliance on sexual reproduction for species propagation.
Gamble, Tony
core   +1 more source

Opacity data for HCN and HNC from a new ab initio line list [PDF]

, 2002
A new extensive ab initio rotation-vibration HCN/HNC line list is presented. The line list contains rotation-vibration energy levels, line frequencies, and line strengths for transitions between states with energy less than 18,000 cm-1 and with J≤60 ...
Harris, G.J., Polyansky, O.L., Tennyson, J.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Kontrak Psikologis Dalam Meningkatkan Perilaku Warga Organisasi Dengan Sikap Kerja Sebagai Mediator [Psychological Contracts in Improving Organizational Citizens Behavior with Work Attitude as a Mediator]

DeReMa (Development Research of Management): Jurnal Manajemen, 2019
This study aims to examine psychological contracts in increasing organizational citizenship behavior with work attitude as a mediator. The psychological contracts identify that employees work effectively if there is a balance between what the ...
Sry Rosita
doaj   +1 more source

Polyunsaturated fatty acids influence offspring sex ratio in cows [PDF]

, 2018
Dietary polyunsaturated fatty acids (PUFAs) can influence fertility in farm animals. Some evidence in mice and sheep have suggested that PUFAs may influence offspring sex ratio, which may have significant value for cattle production.
Abo El-Atta, A M A, El-Harairy, M A, Fouladi-Nashta, A A, Khalil, W A, Marei, W F A, Pushpakumara, P G A, Wathes, D C   +6 more
core   +2 more sources