Results 91 to 100 of about 8,618 (210)

IL‐33 Elicits LTC4 Synthesis in Allergic Inflammation via ST2‐Mediated Activation of Eosinophils

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Allergic reaction‐derived IL‐33 activates ST2 to trigger selective eosinophil activation. IL‐33 in a type 2 immune response environment induces biogenesis of lipid bodies in eosinophils, platforms for the generation of lipid mediators, and selectively triggers LTC4 production.
Vitória F. Rosário‐Garcia, Ericka Guimaraes‐Ferreira, Yasmin Brito‐Leite, Jamille F. Oliveira, Julia Santos‐da‐Silva, Natália R. T. Amorim, Valdirene S. Muniz, Lukas Bolini, Miriam B. F. Werneck, Claudio Canetti, Bruno L. Diaz, Christianne Bandeira‐Melo   +11 more
wiley   +1 more source

Are soluble ST2 levels influenced by vitamin D and/or the seasons?

Endocrine Connections, 2019
Objective: Cardiovascular disease manifestation and several associated surrogate markers, such as vitamin D, have shown substantial seasonal variation.
Vito Francic, Martin Keppel, Verena Schwetz, Christian Trummer, Marlene Pandis, Valentin Borzan, Martin R Grübler, Nicolas D Verheyen, Marcus E Kleber, Graciela Delgado, Angela P Moissl, Benjamin Dieplinger, Winfried März, Andreas Tomaschitz, Stefan Pilz, Barbara Obermayer-Pietsch   +15 more
doaj   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, Volume 6, Issue 1, Page 16-38, March 2026.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

ST2 and IL-33 in pregnancy and pre-eclampsia. [PDF]

PLoS ONE, 2011
Normal pregnancy is associated with a mild systemic inflammatory response and an immune bias towards type 2 cytokine production, whereas pre-eclampsia is characterized by a more intense inflammatory response, associated with endothelial dysfunction and a
Ingrid Granne, Jennifer H Southcombe, James V Snider, Dionne S Tannetta, Tim Child, Christopher W G Redman, Ian L Sargent   +6 more
doaj   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Cardiovascular biomarkers and preeclampsia: A narrative review

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Preeclampsia (PE) is a complex pregnancy disorder linked to cardiovascular disease (CVD) through shared risk factors and epidemiological associations. Cardiovascular biomarkers are valuable for predicting, diagnosing and assessing PE, as well as estimating future CVD risk. This review explores current cardiovascular biomarkers used in clinical practice
Johana Ullmo, Madalina Nicoleta Nan, Mónica Cruz‐Lemini, Carmen Garrido‐Gimenez, Judit Platero, Álvaro García‐Osuna, Pablo García‐Manau, Marcel Twickler, Elisa Llurba   +8 more
wiley   +1 more source

Prognostic biomarker soluble ST2 exhibits diurnal variation in chronic heart failure patients

ESC Heart Failure, 2020
Aim Soluble suppression of tumorigenicity‐2 (sST2) is a strong prognostic biomarker in heart failure. The emerging understanding of circadian biology in cardiovascular disease may lead to novel applications in prognosis and diagnosis and may provide ...
Sandra Crnko, Markella I. Printezi, Tijn P.J. Jansen, Laurynas Leiteris, Manon G. van derMeer, Hilde Schutte, Martijn vanFaassen, Bastiaan C. duPré, Nicolaas deJonge, Folkert W. Asselbergs, Carlo A.J.M. Gaillard, Hans Kemperman, Pieter A. Doevendans, Joost P.G. Sluijter, Linda W. vanLaake   +14 more
doaj   +1 more source

Settlement Calculation of Pile Foundation With Different Shaft Resistance Models by Mean Vertical Additional Stress Coefficient Method

Advances in Civil Engineering, Volume 2026, Issue 1, 2026.
This study develops the mean vertical additional stress coefficient on the basis of vertical additional stress, and an analytical solution for calculating the settlement of pile foundations is derived accordingly. The method simplifies settlement calculations by simply layering the soil layers with different compression moduli, eliminating the need for
Heng Wang, Shuanglong Yang, Francesco Salvatore Liguori   +2 more
wiley   +1 more source

Soluble ST2 for Prediction of Heart Failure and Cardiovascular Death in an Elderly, Community‐Dwelling Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundSoluble ST2 (sST2), a marker of myocyte stretch and fibrosis, has prognostic value in many cardiovascular diseases. We hypothesized that sST2 levels are associated with incident heart failure (HF), including subtypes of preserved (HFpEF) and ...
Ravi H. Parikh, Stephen L. Seliger, Robert Christenson, John S. Gottdiener, Bruce M. Psaty, Christopher R. deFilippi   +5 more
doaj   +1 more source

Assessing the Role of Soluble Suppression of Tumorigenicity‐2 (sST2) in Patients With Pulmonary Embolism

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Background Pulmonary embolism (PE) is a serious cardiovascular condition associated with a wide range of clinical outcomes, from mild symptoms to severe hemodynamic compromise. Existing biomarkers like D‐dimer and proBNP have limitations in specificity and do not fully capture the inflammatory and hemodynamic aspects of the disease. Soluble suppression
Ahmet Seyfeddin Gurbuz, Ahmet Taha Sahin, Serhat Kesriklioglu, Mohammad Rezwan Habib   +3 more
wiley   +1 more source