Results 201 to 210 of about 12,750 (218)

Soluble ST2 (sST2) as potential marker for hepatic cystic echinococcosis activity

Journal of Infection, 2020
this study aims to identify the potential marker for hepatic cystic echinococcosis (CE) activity.totally 97 CE patients and 47 health control (HC) subjects were included. Based on the ultrasound (US) images, CE patients were further categorized as active CE (ACE; 52 cases) and inactive CE (IACE; 45 cases).
Mengting, An, Yuejie, Zhu, Cheng, Xu, Yujiao, Li, Nannan, Pang, Xiao, Zhao, Zhiwei, Li, Hongying, Wang, Fengbo, Zhang, Jianbing, Ding   +9 more
openaire   +2 more sources

Pleural Effusion IL-33/sST2 Levels and Effects of Low and High IL-33/sST2 Levels on Human Mesothelial Cell Adhesion and Migration

Inflammation, 2019
Interleukin 33 (IL-33) is an alarmin with multiple roles in immunity and cell homeostasis, highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). Production of IL-33 and soluble ST2 (sST2), a decoy receptor for IL-33, has been implicated in several pulmonary diseases, but both have been scarcely investigated ...
Ourania S, Kotsiou, Rajesh M, Jagirdar, Eleftherios D, Papazoglou, Chrissi, Hatzoglou, Konstantinos I, Gourgoulianis, Sotirios G, Zarogiannis   +5 more
openaire   +2 more sources

RGS domain-independent Sst2 action

2008
RGS proteins are a family of proteins that share a conserved RGS domain that contacts Gα to accelerate GTP hydrolysis. It is thought that the function of RGS proteins lies not only in the RGS domain, but also through interactions mediated by domains outside of this region.
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Presence of sst2(a) receptor immunoreactivity in rat ependyma and tanycytes

Neuroreport, 2001
Somatostatin sst2(a) receptor was observed, by immunofluorescence, in ependymal cells and in tanycytes of the wall of the ventricle and the hypothalamic recess of the male rat median eminence. Strong immunoreactivity for the receptor protein was observed in lateral tanycytes (alpha-type) while a moderate signal was seen in medial tanycytes (beta-type).
S H, Hashemi, J Y, Li, M, Schindler, A, Dahlström   +3 more
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Fluorescence Aptasensor for sST2 Detection Using In Vitro Selected Aptamers

Analytical Chemistry
Soluble suppression of tumorigenicity 2 (sST2) is a critical biomarker for heart failure (HF) diagnosis and prognosis, yet conventional antibody-based detection methods suffer from time-consuming protocols and high costs and involve complex detection procedures.
Shuqian Qiu, Li Chen, Dongqing Zhuang, Yue Cao, Renli Wei, Xiaoai Cao, Yongshou Chen, Xiaofeng Lai, Shuiliang Wang, Yue Lin, Zhenyu Lin, Shenghang Zhang   +11 more
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Spontaneous Shmooing in Saccharomyces Sans Sst2

Science's STKE, 2003
Yeast release pheromones bind to heterotrimeric guanosine triphosphate (GTP)-binding protein (G protein)-coupled receptors (GPCRs), triggering a mating response in which cells of the opposite mating type extend a projection called a shmoo. The mating response depends on GPCR-stimulated guanine nucleotide exchange on the G protein α subunit (Gα ...
openaire   +1 more source

Agonist properties of putative small-molecule somatostatin sst2 receptor-selective antagonists

European Journal of Pharmacology, 2003
The availability of antagonist ligands for somatostatin receptors is very limited, with those that are available often displaying agonist properties or limited receptor subtype selectivity. Hay et al. [Bioorg. Med. Chem. Lett. 11 (2001) 2731] recently described the development of small-molecule somatostatin receptor subtype 2 (sst(2)) selective ...
Caroline, Nunn, Daniel, Langenegger, Konstanze, Hurth, Kerstin, Schmidt, Dominique, Fehlmann, Daniel, Hoyer   +5 more
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Functional characterisation of the putative somatostatin sst2 receptor antagonist CYN 154806

Naunyn-Schmiedeberg's Archives of Pharmacology, 2003
The two forms (DTyr8 and LTyr8) of the putative somatostatin sst2 receptor antagonist CYN 154806 (Ac-4NO2-Phe-c(DCys-Tyr-DTrp-Lys-Thr-Cys)-D/LTyr-NH2) were investigated on recombinant human somatostatin receptors and endogenous guinea-pig ileum receptors.
Caroline, Nunn, Philippe, Schoeffter, Daniel, Langenegger, Daniel, Hoyer   +3 more
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Presence of somatostatin sst2 receptors in the developing rat auditory system

Developmental Brain Research, 1996
A transient expression of somatostatin mRNA as well as of the peptide itself has been described in the developing mammalian auditory brainstem. However, little is known about the presence, and the spatial and temporal pattern of somatostatin (SRIF) receptor subtypes in this system.
V S, Thoss, M, Kungel, E, Friauf, D, Hoyer   +3 more
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Functional interactions occur between SST2 and SST3 receptor subtypes

2009
Rationale: Previous studies in our lab showed that sst2 and sst3 receptors are implicated in the anticonvulsant actions of somatostatin-14 and cortistatin-14. These findings suggest a possible functional coupling between these two receptors. To confirm this intracellular interaction, we used L-779,976, a selective sst2 agonist, cyanamid154806, a ...
Aourz, Najat, Smolders, Ilse Julia, De Bundel, Dimitri, Portelli, Jeanelle, Michotte, Yvette   +4 more
openaire   +2 more sources