Results 91 to 100 of about 7,850 (192)

Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae

iMeta, Volume 4, Issue 5, October 2025.
The global emergence of hypervirulent, carbapenem‐resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 genomes across 90 years, we uncover a core evolutionary constraint—virulence and resistance rarely coexist without trade‐offs. Potent carbapenemases (blaKPC,
Yuchen Wu, Fan Pu, Zelin Yan, Yanyan Zhang, Kaichao Chen, Shengkai Li, Yuezhuo Wang, Heyuan Lun, Tingting Qu, Jing Wang, Heng Li, Danxia Gu, Sheng Chen, Ping He, Rong Zhang, Zhemin Zhou   +15 more
wiley   +1 more source

Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase–producing Escherichia coli causing bacteremia

Diagnostic Microbiology and Infectious Disease, 2016
We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non ...
Min Kyeong Cha, Cheol-In Kang, So Hyun Kim, Sun Young Cho, Young Eun Ha, Yu Mi Wi, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song   +8 more
openaire   +3 more sources

High Rates of Antimicrobial Resistance and Emergence of High‐Risk Clones in Community‐Acquired Uropathogenic Escherichia coli

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
A total of 98 E. coli isolates from community‐acquired UTIs were analyzed, revealing high resistance rates to trimethoprim‐sulfamethoxazole and fluoroquinolones. Phylogenetic group B2 was the most prevalent and associated with increased virulence, while ST1193 emerged as the dominant MDR clone.
Vívian Santos Galvão, Adriano Souza Santos Monteiro, João Lucas Pinheiro Leite, Isabela Oliveira Sousa, Soraia Machado Cordeiro, Joice Neves Reis   +5 more
wiley   +1 more source

Molecular Characterisation of Escherichia coli Collected From an Urban River in Johannesburg, South Africa

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Escherichia coli isolates from the Jukskei River in Johannesburg, South Africa, are genetically diverse, indicating multiple contamination sources and potential cross‐environmental transmission between the river, humans and livestock. Moreover, the presence of pathogenic E.
Luyanda Mkhize, Musa Marimani, Sanelisiwe Thinasonke Duze   +2 more
wiley   +1 more source

Phylogeny, sequence-typing and virulence profile of uropathogenic Escherichia coli (UPEC) strains from Pakistan

BMC Infectious Diseases, 2019
Background Escherichia coli lineage ST131 predominates across various spectra of extra-intestinal infections, including urinary tract infection (UTI).
Ihsan Ali, Zara Rafaque, Ibrar Ahmed, Faiza Tariq, Sarah E. Graham, Elizabeth Salzman, Betsy Foxman, Javid Iqbal Dasti   +7 more
doaj   +1 more source

Prevalence of E. coli ST131 among Uropathogenic E. coli Isolates from Iraqi Patients in Wasit Province, Iraq

International Journal of Microbiology, 2020
The emergence of Escherichia coli sequence type 131 (E. coli ST131) clone represents a major challenge to public health globally, since this clone is reported as highly virulent and multidrug-resistant, thus making it successfully disseminated worldwide.
Dhifar Raa’d Al-Guranie, Sareaa Maseer Al-Mayahie   +1 more
doaj   +1 more source

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131 [PDF]

, 2016
UNLABELLED: Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli clone worldwide and a major cause of urinary tract and bloodstream infections.
Ben Zakour, NL, Stanton-Cook, M, Roberts, LW, Schembri, MA, Alsheikh-Hussain, AS, Khanh Nhu, NT, Ashcroft, MM, Beatsona, SA   +7 more
core   +3 more sources

Occurrence and spread of carbapenemase‐producing Enterobacterales (CPE) in the food chain in the EU/EFTA. Part 1: 2025 update

EFSA Journal, Volume 23, Issue 4, April 2025.
Abstract Carbapenemase‐producing Enterobacterales (CPE) have been reported in the food chain in 14 out of 30 EU/EFTA countries. Commonly reported genes are blaVIM‐1, blaOXA‐48 and blaOXA‐181, followed by blaNDM‐5 and blaIMI‐1. Escherichia coli, target of most of the studies, Enterobacter cloacae complex, Klebsiella pneumoniae complex and Salmonella ...
EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), Ana Allende, Avelino Álvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Fernando Pérez‐Rodríguez, Panagiotis Skandamis, Elisabetta Suffredini, Hector Argüello, Johan Bengtsson‐Palme, Alessandra Carattoli, Anke Kohlenberg, Dominique L. Monnet, Laurent Poirel, Beatriz Guerra, Raquel García‐Fierro, Ernesto Liébana, Sonagnon Martin Goudjihounde, Núria Ferrer‐Bustins, Hanne Rabbås, Luisa Peixe   +28 more
wiley   +1 more source

Design of a 2D Melting Curve–Based Multiplex PCR Assay for Detection of SARS‐CoV‐2/RSV/Influenza A‐B

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Background Recent advances in detecting respiratory pathogens have allowed for the simultaneous identification of multiple agents, enabling quick and accurate diagnosis to start timely treatment. This study aimed to design a novel two‐dimensional (2D) multiplex reverse transcription quantitative PCR (RT‐qPCR) assay. This assay allows for the concurrent
Murat Sayan, Ayse Arikan, Tahaberk Atesoğlu, Harun Agca   +3 more
wiley   +1 more source

Adherent/invasive Escherichia coli (AIEC) isolates from asymptomatic people: new E. coli ST131 O25:H4/H30-Rx virotypes [PDF]

, 2018
Background The widespread Escherichia coli clone ST131 implicated in multidrug-resistant infections has been recently reported, the majority belonging to O25:H4 serotype and classified into five main virotypes in accordance with the virulence genes ...
Rosa del Carmen Rocha-Gracia, Rocha-Gracia, Rosa Del Carmen [0000-0002-0456-8264], Edwin Barrios-Villa, Ygnacio Martínez-Laguna, Arenas-Hernández, Margarita María De La Paz, Martínez-Laguna, Ygnacio [0000-0002-3222-6624], Barrios-Villa, Edwin, Martínez De La Peña, Claudia Fabiola, Carmen Torres, Lozano-Zaraín, Patricia [0000-0002-1550-4338], Patricia Lozano-Zaraín, Torres, Carmen [0000-0003-3709-1690], Cortés-Cortés, Gerardo, Gerardo Cortés-Cortés, Claudia Fabiola Martínez de la Peña, Margarita María de la Paz Arenas-Hernández   +15 more
core   +1 more source