Results 71 to 80 of about 8,262 (195)

ESBL-producingEscherichia coliST131 versus non-ST131: evolution and risk factors of carriage among French children in the community between 2010 and 2015 [PDF]

Journal of Antimicrobial Chemotherapy, 2016
The objective of this study was to evaluate the evolution and risk factors of ESBL-producing Enterobacteriaceae (ESBL-E) carriage in children in the community for a long period distinguishing ST131 and non-ST131 Escherichia coli.In this prospective study, rectal samples were obtained from children aged 6-24 months by community paediatricians between ...
André, Birgy, Corinne, Levy, Philippe, Bidet, Franck, Thollot, Véronique, Derkx, Stéphane, Béchet, Patricia, Mariani-Kurkdjian, Robert, Cohen, Stéphane, Bonacorsi   +8 more
openaire   +2 more sources

A Nosocomial Respiratory Infection Outbreak of Carbapenem-Resistant Escherichia coli ST131 With Multiple Transmissible blaKPC–2 Carrying Plasmids

Frontiers in Microbiology, 2020
Escherichia coli sequence type 131 (ST131) is well known for its multidrug resistance profile. Carbapenems have been considered the treatment of choice for E.
Lin Gong, Lin Gong, Na Tang, Na Tang, Dongke Chen, Kaiwen Sun, Ruiting Lan, Wen Zhang, Haijian Zhou, Min Yuan, Xia Chen, Xiaofei Zhao, Jie Che, Xuemei Bai, Yunfei Zhang, Hongtao Xu, Timothy R. Walsh, Jinxing Lu, Jianguo Xu, Juan Li, Jie Feng   +20 more
doaj   +1 more source

Integrative Modular, Network‐Based, and Machine Learning Framework for Predicting Accessory Genome Functions and Virulence in Escherichia coli O157:H7

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
An analysis of the accessory genomes from 77 Escherichia coli O157:H7 strains using network and machine learning techniques uncovers modular communities of plasmid‐related virulence associated with IncF replicons. Accessory markers that are not directly linked to toxin genes can effectively predict the virulence status with an AUC of 0.85, facilitating
Sydney Menzeko Gambushe, Oliver Tendayi Zishiri   +1 more
wiley   +1 more source

Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis [PDF]

, 2016
OBJECTIVES: Observational studies have suggested that Escherichia coli sequence type (ST) 131 and Klebsiella pneumoniae ST258 have hyperendemic properties.
Haverkate, M R, Bonten, M J M, Bootsma, M C J, Mathematical Modeling, Dautzenberg, M J D, Sub Mathematical Modeling   +5 more
core   +3 more sources

ESBL-Producing and Non-ESBL-Producing Escherichia coli Isolates from Urinary Tract Differ in Clonal Distribution, Virulence Gene Content and Phylogenetic Group

Infection and Drug Resistance, 2023
Yewei Fang,1 Shuan Tao,2 Huimin Chen,2 Yao Xu,3 Luyan Chen,4 Wei Liang1 1Department of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo, People’s Republic of China; 2School of Medicine, Jiangsu University, Zhejiang, People ...
Fang Y, Tao S, Chen H, Xu Y, Chen L, Liang W   +5 more
doaj  

Separate F-Type Plasmids Have Shaped the Evolution of the H30 Subclone of Escherichia coli Sequence Type 131

mSphere, 2016
The extraintestinal pathogenic Escherichia coli (ExPEC) H30 subclone of sequence type 131 (ST131-H30) has emerged abruptly as a dominant lineage of ExPEC responsible for human disease.
Timothy J. Johnson, Jessica L. Danzeisen, Bonnie Youmans, Kyle Case, Katharine Llop, Jeannette Munoz-Aguayo, Cristian Flores-Figueroa, Maliha Aziz, Nicole Stoesser, Evgeni Sokurenko, Lance B. Price, James R. Johnson   +11 more
doaj   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

Genes in Escherichia coli ST131 [PDF]

, 2023
Escherichia coli sequence type 131 (ST131) has contributed to the spread of extended-spectrum beta-lactamase (ESBL) and has emerged as the dominant cause of hospital- and community-acquired urinary tract infections.
Ter-Stepanyan, M.M., Mary M. Ter-Stepanyan, Cave, Rory J., Hermine V. Mkrtchyan, Rory Cave, Mkrtchyan, Hermine   +5 more
core   +1 more source

High Metabolic Potential May Contribute to the Success of ST131 Uropathogenic Escherichia coli [PDF]

Journal of Clinical Microbiology, 2012
ABSTRACT Uropathogenic Escherichia coli (UPEC) is the predominant cause of urinary tract infection in both hospital and community settings. The recent emergence of multidrug-resistant clones like the O25b:H4-ST131 lineage represents a significant threat to health, and numerous studies have explored the ...
Gibreel, Tarek M., Dodgson, Andrew R., Cheesbrough, John, Bolton, Frederick J., Fox, Andrew J., Upton, Mathew   +5 more
openaire   +3 more sources

Overexpression of Escherichia coli yaiX Confers Multidrug Resistance and Enhances Virulence in the Silkworm Infection Model

Microbiology and Immunology, Volume 70, Issue 4, Page 193-205, April 2026.
ABSTRACT The emergence of bacteria with both antimicrobial resistance and high virulence has become a global health concern, underscoring the urgent need to elucidate the molecular basis underlying these traits. Here, we employed the silkworm (Bombyx mori) infection model, which is suitable for high‐throughput screening, together with an Escherichia ...
Kinuka Hongu, Kazuya Ishikawa, Tomoki Kosaki, Shin‐Ichi Miyoshi, Kazuyuki Furuta, Chikara Kaito   +5 more
wiley   +1 more source