Results 61 to 70 of about 8,497 (168)

First Identification of a Patient with Prosthesis-Related Infection Caused by an MCR-1.1-Producing ST131 Escherichia coli After Rhinoplasty

Infection and Drug Resistance, 2021
Zhehao Li,1,* Ran Shi,1,* Hao Wu,2,* Ping Yan3 1Department of Plastic and Reconstructive Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China; 2Department of Otolaryngology, Hospital of ...
Li Z, Shi R, Wu H, Yan P
doaj  

Integrative Modular, Network‐Based, and Machine Learning Framework for Predicting Accessory Genome Functions and Virulence in Escherichia coli O157:H7

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
An analysis of the accessory genomes from 77 Escherichia coli O157:H7 strains using network and machine learning techniques uncovers modular communities of plasmid‐related virulence associated with IncF replicons. Accessory markers that are not directly linked to toxin genes can effectively predict the virulence status with an AUC of 0.85, facilitating
Sydney Menzeko Gambushe, Oliver Tendayi Zishiri   +1 more
wiley   +1 more source

Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131- H 30Rx and ST131- H 30R1 Strains [PDF]

, 2017
Escherichia coli sequence type 131 (ST131) predominates globally among multidrug-resistant (MDR) E. coli strains. We used whole-genome sequencing (WGS) to investigate 63 MDR E. coli isolates from 7 North Carolina community hospitals (2010 to 2015).
Kanamori, Hajime, Parobek, Christian M., Johnson, James R., Weber, David J., Anderson, Deverick J., Johnson, Timothy J., Rutala, William A., Johnston, Brian D., Juliano, Jonathan J.   +8 more
core   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

The genotypic and phenotypic characteristics contributing to high virulence and antibiotics resistance in Escherichia coli O25-B2-ST131 in comparison to non- O25-B2-ST131

BMC Pediatrics, 2023
Background Escherichia coli serogroup O25b-sequence type 131 (E. coli O25-B2-ST131) is considered as multidrug-resistant and hypervirulent organism. There is lack of data about involvement of this pathogen in the children’s infection.
Razieh Shahbazi, Siavosh Salmanzadeh-Ahrabi, Mohammad Mehdi Aslani, Masoud Alebouyeh, Jamal Falahi, Vajihe Sadat Nikbin   +5 more
doaj   +1 more source

Overexpression of Escherichia coli yaiX Confers Multidrug Resistance and Enhances Virulence in the Silkworm Infection Model

Microbiology and Immunology, Volume 70, Issue 4, Page 193-205, April 2026.
ABSTRACT The emergence of bacteria with both antimicrobial resistance and high virulence has become a global health concern, underscoring the urgent need to elucidate the molecular basis underlying these traits. Here, we employed the silkworm (Bombyx mori) infection model, which is suitable for high‐throughput screening, together with an Escherichia ...
Kinuka Hongu, Kazuya Ishikawa, Tomoki Kosaki, Shin‐Ichi Miyoshi, Kazuyuki Furuta, Chikara Kaito   +5 more
wiley   +1 more source

Emergence and spread of O16-ST131 and O25b-ST131 clones among faecal CTX-M-producing Escherichia coli in healthy individuals in Hunan Province, China.

, 2015
OBJECTIVES The objectives of this study were to determine CTX-M-producing Escherichia coli ST131 strain prevalence in stool specimens from healthy subjects in central China and to molecularly characterize clonal groups.
Jian, Zi-Juan, Liang, Xiang-Hui, Hawkey, Peter M, Li, Yan-Ming, Zhong, Yi-Ming, Liu, Wen-En   +5 more
core   +1 more source

Escherichia coli ST131-H22 as a Foodborne Uropathogen

mBio, 2018
Escherichia coli sequence type 131 (ST131) has emerged rapidly to become the most prevalent extraintestinal pathogenic E. coli clones in circulation today.
Cindy M. Liu, Marc Stegger, Maliha Aziz, Timothy J. Johnson, Kara Waits, Lora Nordstrom, Lori Gauld, Brett Weaver, Diana Rolland, Sally Statham, Joseph Horwinski, Sanjeev Sariya, Gregg S. Davis, Evgeni Sokurenko, Paul Keim, James R. Johnson, Lance B. Price   +16 more
doaj   +1 more source

Multidrug‐Resistant Pathogen Clonal Spread in Nigeria: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim The rapid dissemination of multidrug‐resistant (MDR) bacterial clones poses a global health threat and limits treatment options. Understanding the dynamics of bacterial clones in Nigeria is essential for developing effective control strategies. This systematic review aimed to track MDR pathogen clones in Nigeria. Methods The
Emmanuel N. Ugbo, Felicitas N. Afiukwa, Mustofa H. Effendi, Samuel Darkwah, Alex Odoom, Eric S. Donkor   +5 more
wiley   +1 more source

Multidrug-resistant extraintestinal pathogenic Escherichia coli of sequence type ST131 in animals and foods

, 2011
Multidrug-resistant Escherichia coli sequence type 131 (ST131) has recently emerged as a globally distributed cause of extraintestinal infections in humans.
James R. Johnson, Cobbold, Rowland N., Joanne L. Platell, Johnson, J., Rowland N. Cobbold, Cobbold, R., Johnson, James R., Trott, D., Darren J. Trott, Trott, Darren J., Platell, J., Platell, Joanne L.   +11 more
core   +1 more source