Results 31 to 40 of about 6,268 (156)

Phenotypic microarrays suggest Escherichia coli ST131 is not a metabolically distinct lineage of extra-intestinal pathogenic E. coli. [PDF]

PLoS ONE, 2014
Extraintestinal pathogenic E. coli (ExPEC) are the major aetiological agent of urinary tract infections (UTIs) in humans. The emergence of the CTX-M producing clone E. coli ST131 represents a major challenge to public health worldwide.
Abdulaziz Alqasim, Richard Emes, Gemma Clark, Jane Newcombe, Roberto La Ragione, Alan McNally   +5 more
doaj   +1 more source

Resistome and Virulome of Multi-Drug Resistant E. coli ST131 Isolated from Residents of Long-Term Care Facilities in the Northern Italian Region

Diagnostics, 2022
Long-term care facilities (LTCFs) are important reservoirs of antimicrobial-resistant (AMR) bacteria which colonize patients transferred from the hospital, or they may emerge in the facility as a result of mutation or gene transfer. In the present study,
Sabrina Cherubini, Mariagrazia Perilli, Anna Maria Azzini, Evelina Tacconelli, Laura Maccacaro, Alda Bazaj, Laura Naso, Gianfranco Amicosante, LTCF-Veneto Working Group, Giuliana Lo Cascio, Alessandra Piccirilli   +10 more
doaj   +1 more source

Gut microbiome predictors of Escherichia coli sequence type 131 colonization and lossResearch in context

EBioMedicine
Summary: Background: Escherichia coli sequence type 131 (ST131), specifically its fluoroquinolone-resistant H30R clade (ST131-H30R), is a global multidrug-resistant pathogen.
Daniel E. Park, Maliha Aziz, Benjamin J. Koch, Kelsey Roach, Connie Clabots, James R. Johnson, Lance B. Price, Cindy M. Liu   +7 more
doaj   +1 more source

Separate F-Type Plasmids Have Shaped the Evolution of the H30 Subclone of Escherichia coli Sequence Type 131

mSphere, 2016
The extraintestinal pathogenic Escherichia coli (ExPEC) H30 subclone of sequence type 131 (ST131-H30) has emerged abruptly as a dominant lineage of ExPEC responsible for human disease.
Timothy J. Johnson, Jessica L. Danzeisen, Bonnie Youmans, Kyle Case, Katharine Llop, Jeannette Munoz-Aguayo, Cristian Flores-Figueroa, Maliha Aziz, Nicole Stoesser, Evgeni Sokurenko, Lance B. Price, James R. Johnson   +11 more
doaj   +1 more source

Molecular determination of O25b/ST131 clone type among extended spectrum β-lactamases production Escherichia coli recovering from urinary tract infection isolates

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Escherichia coli (E. coli) O25b/ST131 clone causes urinary tract infection (UTI) and is associated with a broad spectrum of other infections, such as intra-abdominal and soft tissue infections, that can be affecting bloodstream infections ...
Amin Khoshbayan, Rezvan Golmoradi Zadeh, Majid Taati Moghadam, Shiva Mirkalantari, Atieh Darbandi   +4 more
doaj   +1 more source

Antibacterial Potential of Actinomycete Extracts and Characterization of β‐Lactamase‐Producing Multidrug‐Resistant Uropathogenic Escherichia coli

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Antibacterial Potential of Actinomycete Extracts Against Multidrug‐Resistant Escherichia coli in Babil Province, Iraq. ABSTRACT The increasing prevalence of multidrug‐resistant (MDR) uropathogenic Escherichia coli (UPEC) strains, particularly those producing β‐lactamase enzymes, complicates urinary tract infection (UTI) treatment and poses a ...
Hoda Khaledi, Nour Oude Obeid
wiley   +1 more source

Detection of blaNDM‐1 and blaIMP‐1 Metallo‐β‐Lactamases in Meropenem‐Resistant Clinical Escherichia coli Isolates Using Modified Carbapenem Inactivation Method (mCIM) and PCR Techniques

Journal of Clinical Laboratory Analysis, Volume 39, Issue 21, November 2025.
This study examines the prevalence of blaNDM‐1 and blaIMP‐1 metallo‐β‐lactamase genes in meropenem‐resistant Escherichia coli isolates using mCIM and PCR. The results indicate a higher prevalence of blaNDM‐1 and suggest the presence of alternative resistance mechanisms in some strains, emphasizing the need for further research on antimicrobial ...
Mehdi Roshdi Maleki
wiley   +1 more source

High Emergence of Multidrug-Resistant Sequence Type 131 Subclade C2 among Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli Isolated from the University Hospital Bratislava, Slovakia

Antibiotics, 2023
The expansion of sequence type 131 (ST131) extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli) represents major worldwide challenges. E. coli strains originating from healthcare facilities (labeled No. 1 and No. 2) of the University
Ján Koreň, Michal Andrezál, Elham Ozaee, Hana Drahovská, Martin Wawruch, Adriána Liptáková, Tibor Maliar   +6 more
doaj   +1 more source

Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae

iMeta, Volume 4, Issue 5, October 2025.
The global emergence of hypervirulent, carbapenem‐resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 genomes across 90 years, we uncover a core evolutionary constraint—virulence and resistance rarely coexist without trade‐offs. Potent carbapenemases (blaKPC,
Yuchen Wu, Fan Pu, Zelin Yan, Yanyan Zhang, Kaichao Chen, Shengkai Li, Yuezhuo Wang, Heyuan Lun, Tingting Qu, Jing Wang, Heng Li, Danxia Gu, Sheng Chen, Ping He, Rong Zhang, Zhemin Zhou   +15 more
wiley   +1 more source

High Rates of Antimicrobial Resistance and Emergence of High‐Risk Clones in Community‐Acquired Uropathogenic Escherichia coli

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
A total of 98 E. coli isolates from community‐acquired UTIs were analyzed, revealing high resistance rates to trimethoprim‐sulfamethoxazole and fluoroquinolones. Phylogenetic group B2 was the most prevalent and associated with increased virulence, while ST1193 emerged as the dominant MDR clone.
Vívian Santos Galvão, Adriano Souza Santos Monteiro, João Lucas Pinheiro Leite, Isabela Oliveira Sousa, Soraia Machado Cordeiro, Joice Neves Reis   +5 more
wiley   +1 more source