Results 81 to 90 of about 12,435 (241)

Bacteriophage as a novel therapeutic approach for killing multidrug-resistant Escherichia coli ST131 clone

Frontiers in Microbiology
The emergence of the multidrug-resistant (MDR) Escherichia coli ST131 clone has significantly impacted public health. With traditional antibiotics becoming less effective against MDR bacteria, there is an urgent need for alternative treatment options ...
Md Shamsuzzaman, Shukho Kim, Jungmin Kim
semanticscholar   +1 more source

Hospital-diagnosed infections with Escherichia coli clonal group ST131 are mostly acquired in the community

Scientific Reports, 2021
The worldwide spread of E. coli ST131 has significantly contributed to the dissemination of E. coli producing extended-spectrum β-lactamases (ESBL). In a French University hospital, we assessed the molecular features of ESBL-producing E.
A. Muller, H. Gbaguidi-Haore, P. Cholley, D. Hocquet, M. Sauget, X. Bertrand   +5 more
semanticscholar   +1 more source

NanoMLST: A High‐Throughput Bacterial Multi‐Locus Sequence Typing Workflow Using Oxford Nanopore Next‐Generation Sequencing for ESKAPE + E Pathogens

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
NanoMLST is a workflow suggested as a viable alternative to high‐throughput ST determination for ESKAPE + E pathogens using ONT next‐generation sequencing. ABSTRACT Multi‐Locus Sequence Typing (MLST) is a key method for allocation of Sequence Types (STs) for bacterial isolates. Traditionally, this is performed by the Sanger sequencing method, which can
Isabel García‐Pérez, Fernando Lázaro‐Perona, Diana Soledad Reyes‐Zuñagua, Jared Sotelo, María Rodríguez‐Tejedor, Javier E. Cañada‐García, Iván Bloise, Sergio Martin Portugués‐Rodríguez, Jesús Mingorance, Jesús Oteo‐Iglesias, Elias Dahdouh   +10 more
wiley   +1 more source

Novel genes associated with enhanced motility of Escherichia coli ST131

PLOS ONE, 2017
Uropathogenic Escherichia coli (UPEC) is the cause of ~75% of all urinary tract infections (UTIs) and is increasingly associated with multidrug resistance. This includes UPEC strains from the recently emerged and globally disseminated sequence type 131 (ST131), which is now the dominant fluoroquinolone-resistant UPEC clone worldwide. Most ST131 strains
Asha Kakkanat, Minh-Duy Phan, Alvin W. Lo, Scott A. Beatson, Mark A. Schembri   +4 more
openaire   +5 more sources

Comprehensive analysis of type 1 fimbriae regulation in fimB -null strains from the multidrug resistant Escherichia coli ST131 clone [PDF]

, 2016
Summary\ud \ud Uropathogenic Escherichia coli (UPEC) of sequence type 131 (ST131) are a pandemic multidrug resistant clone associated with urinary tract and bloodstream infections.
Beatson, SA, Lo, AW, Paterson, DL, Peters, KM, Phan, M-D, Roberts, LW, Sarkar, S, Schembri, MA, Tan, L, Totsika, M, Ulett, GC, Upton, M   +11 more
core   +3 more sources

Evolution of ceftazidime-avibactam and cefiderocol resistance in ST131-H30R1-Escherichia coli isolates with KPC-3 mutants and application of FTIR biotyping

Microbiology spectrum
Ceftazidime-avibactam and cefiderocol represent two of the few alternatives for infections by KPC-producing Enterobacterales. We reported the emergence of resistance to both ceftazidime-avibactam and cefiderocol in a KPC-producing ST131-Escherichia coli (
Juan Antonio Castillo-Polo, M. Hernández-García, Ainhize Maruri-Aransolo, Carmen de la Vega, P. Ruiz-Garbajosa, R. Cantón   +5 more
semanticscholar   +1 more source

Detection of blaNDM‐1 and blaIMP‐1 Metallo‐β‐Lactamases in Meropenem‐Resistant Clinical Escherichia coli Isolates Using Modified Carbapenem Inactivation Method (mCIM) and PCR Techniques

Journal of Clinical Laboratory Analysis, Volume 39, Issue 21, November 2025.
This study examines the prevalence of blaNDM‐1 and blaIMP‐1 metallo‐β‐lactamase genes in meropenem‐resistant Escherichia coli isolates using mCIM and PCR. The results indicate a higher prevalence of blaNDM‐1 and suggest the presence of alternative resistance mechanisms in some strains, emphasizing the need for further research on antimicrobial ...
Mehdi Roshdi Maleki
wiley   +1 more source

Clinical isolates of ST131 blaOXA-244-positive Escherichia coli, Italy, December 2022 to July 2023

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
The dissemination of carbapenemase-producing Escherichia coli, although still at low level, should be continuously monitored. OXA-244 is emerging in Europe, mainly in E. coli.
Aurora Piazza, M. Corbella, V. Mattioni Marchetti, C. Merla, I. Mileto, A. Kuka, G. Petazzoni, S. Gaiarsa, R. Migliavacca, F. Baldanti, P. Cambieri   +10 more
semanticscholar   +1 more source

Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae

iMeta, Volume 4, Issue 5, October 2025.
The global emergence of hypervirulent, carbapenem‐resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 genomes across 90 years, we uncover a core evolutionary constraint—virulence and resistance rarely coexist without trade‐offs. Potent carbapenemases (blaKPC,
Yuchen Wu, Fan Pu, Zelin Yan, Yanyan Zhang, Kaichao Chen, Shengkai Li, Yuezhuo Wang, Heyuan Lun, Tingting Qu, Jing Wang, Heng Li, Danxia Gu, Sheng Chen, Ping He, Rong Zhang, Zhemin Zhou   +15 more
wiley   +1 more source

When Carbapenem-Hydrolyzing β-Lactamase KPC Meets Escherichia coli ST131 in France [PDF]

Antimicrobial Agents and Chemotherapy, 2011
Carbapenem resistance in Escherichia coli isolates, though rare, can be attributed to outer membrane protein deficiency coupled with plasmid-mediated extended-spectrum β-lactamases (ESBLs) or class C β-lactamases ([2][1], [10][2], [11][3]) or to carbapenemases. The latter can be either metallo-β-
Naas, T., Cuzon, G., Gaillot, O., Courcol, R., Nordmann, P.   +4 more
openaire   +2 more sources