Results 71 to 80 of about 5,604,642 (305)

Dynamics of Marburg virus in the presence of burial and cremation practices: A fractional approach [PDF]

Mathematics and Computational Sciences
Infectious diseases have long posed a significant threat to the smooth functioning of society. To mitigate their devastating impact, we have conducted a qualitative study of the Marburg virus (MARV) transmission using a novel fractional-order model.
Kaushal Soni, Shyamsunder Kumawat, Arvind Sinha   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Corrigendum: Identification of circRNA biomarker for gastric cancer through integrated analysis

Frontiers in Molecular Biosciences, 2023
Md. Tofazzal Hossain, Md. Tofazzal Hossain, Md. Tofazzal Hossain, Song Li, Md. Selim Reza, Md. Selim Reza, Shengzhong Feng, Xiaojing Zhang, Zhe Jin, Yanjie Wei, Yin Peng   +10 more
doaj   +1 more source

Mathematical Model for Economic Growth, Corruption and Unemployment: Analysis of the Effects of a Time Delay in the Economic Growth

AppliedMath
In this article, we propose a nonlinear mathematical model that incorporates a discrete time delay. The model is used to analyze the dynamics of a socioeconomic system that includes economic growth, corruption, and unemployment.
Ogochukwu Ifeacho, Gilberto González-Parra   +1 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Fractional Optimal Control Problem and Stability Analysis of Rumor Spreading Model with Effective Strategies

Mathematics
This study establishes a fractional-order model (FOM) to describe the rumor spreading process. Members of society in this FOM are classified into three categories that change with time—the population that is ignorant of the rumors and does not know them,
Hegagi Mohamed Ali, Saud Owyed, Ismail Gad Ameen   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Numerical Modeling of Levee Failure Mechanisms by Integrating Seepage and Stability Processes

GeoHazards
Levee failures caused by prolonged flooding and elevated upstream water levels pose a significant risk to floodplain communities, especially as the number of extreme hydrological events increases under climate change.
Liaqat Ali, Shiro Konno, Yoshiya Igarashi, Norio Tanaka   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Mathematical Modeling and Stability Analysis of Agri-Food Tomato Supply Chains via Compartmental Analysis

World
Agri-food supply chains have experienced notable changes in recent decades, with tomatoes (Solanum lycopersicum) maintaining their status as a key global crop in terms of both production and consumption.
Israel Benítez-García, Yasser A. Davizón, Carlos Hernandez-Santos, Nain de la Cruz, Amadeo Hernandez, Aureliano Quiñonez-Ruiz, Eric D. Smith, Jaime Sánchez-Leal, Neale R. Smith   +8 more
doaj   +1 more source