Results 81 to 90 of about 5,632,576 (328)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Fractional Optimal Control Problem and Stability Analysis of Rumor Spreading Model with Effective Strategies

open access: yesMathematics
This study establishes a fractional-order model (FOM) to describe the rumor spreading process. Members of society in this FOM are classified into three categories that change with time—the population that is ignorant of the rumors and does not know them,
Hegagi Mohamed Ali   +2 more
doaj   +1 more source

Aeromechanical stability analysis of COPTER [PDF]

open access: yes
A plan was formed for developing a comprehensive, second-generation system with analytical capabilities for predicting performance, loads and vibration, handling qualities, aeromechanical stability, and acoustics.
Yen, Jing G., Yin, Sheng K.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Numerical Modeling of Levee Failure Mechanisms by Integrating Seepage and Stability Processes

open access: yesGeoHazards
Levee failures caused by prolonged flooding and elevated upstream water levels pose a significant risk to floodplain communities, especially as the number of extreme hydrological events increases under climate change.
Liaqat Ali   +3 more
doaj   +1 more source

An Approach to Performing Stability Analysis for Power Transformer Differential Protection: A Case Study [PDF]

open access: gold, 2022
Muhammad Sheryar   +6 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Mathematical Modeling and Stability Analysis of Agri-Food Tomato Supply Chains via Compartmental Analysis

open access: yesWorld
Agri-food supply chains have experienced notable changes in recent decades, with tomatoes (Solanum lycopersicum) maintaining their status as a key global crop in terms of both production and consumption.
Israel Benítez-García   +8 more
doaj   +1 more source

Stability and Ultimate Load of Three-Layered Plates – A Parametric Study

open access: yesEngineering Transactions, 2003
This work deals with the analysis of influence of some geometrical and material parameters of layers on the mass, critical stress and ultimate load of three-layered plates. The plates are built of metal outer layers and a composite core.
R. Grądzki, K. Kowal-Michalska
doaj   +1 more source

Analysis of the Dynamic Stability Positioning Control System of Semisubmersible [PDF]

open access: yes, 2015
The semisubmersible offshore dynamics depend on the condition of the ocean environments. Disruption of forces and moments in the floating structure caused by environment factors, there are wind, waves and ocean currents.
Aisjah, A. S. (Aulia)   +3 more
core  

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