Results 61 to 70 of about 1,782,799 (317)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Stability of networked control systems based on switched technique

open access: yes, 2003
In this paper we discuss the stability of networked control systems where the networked-induced delay tau(k) is not constant. We introduce some novel concepts and design feedback matrices K-i and a switched strategy among them.
Yu HB(于海斌), Liu YZ(刘玉忠)
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Considerations on Active Control of Crosswind Stability of Railway Vehicles

open access: yes, 2013
The DLR research project Next Generation Train deals with concepts, methods and technologies for a very high-speed train in double deck configuration and light-weight design.
Kurzeck, Bernhard   +3 more
core   +1 more source

Stability in controlled L–theory [PDF]

open access: yesGeometry and Topology Monographs, 2006
This is the version published by Geometry & Topology Monographs on 22 April ...
Pedersen, Erik K., Yamasaki, Masayuki
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Amidst centralized and distributed frequency control in power systems

open access: yes, 2016
We propose a novel frequency control approach in between centralized and distributed architectures, that is a generalized continuous-time feedback control version of the dual decomposition optimization method.
GRAMMATICO, SERGIO   +7 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Robust yaw stability control of hybrid electric vehicles [PDF]

open access: yes, 2014
Yaw stability of an automotive vehicle in a various maneuvers is critical to the overall safety of the vehicle. Robust yaw stability control for a Through-the-Road Hybrid Electric Vehicle (TtR-HEV) with two in–wheel–motors in rear wheels is proposed ...
Kamil, Mudhafar Salah
core  

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