Results 71 to 80 of about 59,164,884 (301)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
A Dual Forgetting Factor-Based Adaptive IMM-UKF Algorithm for Vehicle Tracking
IEEE AccessIn response to the limitations of the traditional Interacting Multiple Model Unscented Kalman Filter (IMM-UKF) in high-noise environments—particularly its insufficient tracking accuracy and poor adaptability of the noise covariance matrices—
Jiaye Xie
doaj +1 more source
On the behavior of EMD and MEMD in presence of symmetric alpha-stable noise [PDF]
, 2014 EmpiricalMode Decomposition (EMD) and its extended versions such as Multivariate EMD (MEMD) are data-driven techniques that represent nonlinear and non-stationary data as a sum of a finite zero-mean AM-FM components referred to as Intrinsic Mode ...
NOLAN, John +4 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Noise robustness of persistent homology on greyscale images, across filtrations and signatures.
PLoS ONE, 2021 Topological data analysis is a recent and fast growing field that approaches the analysis of datasets using techniques from (algebraic) topology. Its main tool, persistent homology (PH), has seen a notable increase in applications in the last decade ...
Renata Turkeš +3 more
doaj +1 more source
, 2004 The noise can stabilize a fluctuating or a periodically driven metastable state in such a way that the system remains in this state for a longer time than in the absence of white noise. This is the noise enhanced stability phenomenon, observed experimentally and numerically in different physical systems. After shortly reviewing all the physical systems
SPAGNOLO, Bernardo +2 more
openaire +3 more sources
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
SNR Degradation in Undersampled Phase Measurement Systems
Sensors, 2016 A wide range of measuring applications rely on phase estimation on sinusoidal signals. These systems, where the estimation is mainly implemented in the digital domain, can generally benefit from the use of undersampling to reduce the digitizer and ...
David Salido-Monzú +3 more
doaj +1 more source
Stability and noise in biochemical switches
, 2000 Many processes in biology, from the regulation of gene expression in bacteria to memory in the brain, involve switches constructed from networks of biochemical reactions. Crucial molecules are present in small numbers, raising questions about noise and stability.
openaire +3 more sources
Euclidean partitions optimizing noise stability
Electronic Journal of Probability, 2014 The Standard Simplex Conjecture of Isaksson and Mossel asks for the partition $\{A_{i}\}_{i=1}^{k}$ of $\mathbb{R}^{n}$ into $k\leq n+1$ pieces of equal Gaussian measure of optimal noise stability. That is, for $ρ>0$, we maximize $$ \sum_{i=1}^{k}\int_{\mathbb{R}^{n}}\int_{\mathbb{R}^{n}}1_{A_{i}}(x)1_{A_{i}}(xρ+y\sqrt{1-ρ^{2}}) e^{-(x_{1}^{2 ...
openaire +3 more sources