Results 81 to 90 of about 59,164,884 (301)
Several results concerning asymptotical mean square stability of equilibria of specific linear stochastic systems are presented and proven. These discrete time systems can be interpreted as numerical solution of stochastic differential equations driven ...
Schurz, Henri
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Stochastic stability of an autoresonance model with a center–saddle bifurcation [PDF]
The purpose of this work is to investigate the effect of stochastic perturbations of the white noise type on the stability of capture into autoresonance in oscillating systems with a variable pumping amplitude and frequency such that a center&ndash ...
Sultanov, Oskar Anvarovich
doaj +1 more source
Cell signalling stabilizes morphogenesis against noise [PDF]
Abstract Embryonic development involves gene networks, extracellular signaling, cell behaviors (cell division, apoptosis, adhesion, etc.) and mechanical interactions. How should gene networks, extracellular signaling and cell behaviors be coordinated to lead to complex and robust morphologies?
Pascal F. Hagolani +3 more
openaire +5 more sources
Including orbital fluctuations in the noise spectrum of autonomous circuits [PDF]
We discuss the impact of orbital fluctuations on the noise spectrum of a free-running oscillator, exploiting a rigorous nonlinear perturbative analysis based on the Floquet theory, and providing evidence of its relevance for high-Q oscillators.
Bonani, Fabrizio +3 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanisms of genetic regulatory networks to attenuate the molecular noise to ...
Wang Yu-Chao, Chen Bor-Sen
doaj +1 more source
Noise Stability of Ranked Choice Voting
We conjecture that Borda count is the ranked choice voting method that best preserves the outcome of an election with randomly corrupted votes, among all fair voting methods with small influences satisfying the Condorcet Loser Criterion. This conjecture is an adaptation of the Plurality is Stablest Conjecture to the setting of ranked choice voting ...
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

