Results 61 to 70 of about 59,164,884 (301)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Persistence and Stochastic Extinction in a Lotka–Volterra Predator–Prey Stochastically Perturbed Model

Mathematics
The classical Lotka–Volterra predator–prey model is globally stable and uniformly persistent. However, in real-life biosystems, the extinction of species due to stochastic effects is possible and may occur if the magnitudes of the stochastic effects are ...
Leonid Shaikhet, Andrei Korobeinikov
doaj   +1 more source

Penerapan Metode Monte-Carlo untuk Analisis Toleransi Perubahan Nilai Komponen Terhadap Kinerja Osilator Frekuensi 2,3 GHz

Jurnal Rekayasa Elektrika, 2017
In telecommunications equipment, an oscillator has a function to generate a carrier signal. As the carrier signal, a high stability performance is required. The frequency shift caused by component tolerances.
Teguh Firmansyah, Gunawan Wibisono
doaj   +1 more source

Lyapunov Based Observer Design for Electro-Hydraulic Arm System

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2022
In this paper, a Lyapunov based observer design is proposed to observe the load pressure of electro-hydraulic arm systems. The stability of the observer is investigated by using the Lyapunov based method.
Mithat Önder, Alper Bayrak, Serkan Aksoy   +2 more
doaj   +1 more source

Extreme levels of noise constitute a key neuromuscular deficit in the elderly [PDF]

, 2012
Fluctuations during isometric force production tasks occur due to the inability of musculature to generate purely constant submaximal forces and are considered to be an estimation of neuromuscular noise.
William R Taylor, Navrag B. Singh, Singh Navrag B., Singh, Navrag; id_orcid, Singh, Navrag B., Niklas König, Markus O Heller, Adamantios Arampatzis, Heller Markus O., Taylor, William R., König Niklas, König, Niklas, Taylor William R., William R. Taylor, Markus O. Heller, Arampatzis, Adamantios, Taylor, William R.; id_orcid, Arampatzis Adamantios, Heller, Markus O., Navrag B Singh, Ignasiak, Niklas König   +20 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

An Improved Gaussian Sum Extended Kalman Filter With Colored Noise for GNSS/SINS Tightly Coupled Positioning and Attitude Determination Systems

IEEE Access
The Gaussian sum extended Kalman filter (GSEKF), as a nonlinear non-Gaussian filter, disregards the impact of colored noise components in non-Gaussian noise engendered by external interference, which may compromise the estimation accuracy in global ...
Qing Dai, Guorui Xiao, Ru Wan, Shenghui Li   +3 more
doaj   +1 more source

Noise performance of frequency modulation Kelvin force microscopy

Beilstein Journal of Nanotechnology, 2014
Noise performance of a phase-locked loop (PLL) based frequency modulation Kelvin force microscope (FM-KFM) is assessed. Noise propagation is modeled step by step throughout the setup using both exact closed loop noise gains and an approximation known as “
Heinrich Diesinger, Dominique Deresmes, Thierry Mélin   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

High-Noise Grayscale Image Denoising Using an Improved Median Filter for the Adaptive Selection of a Threshold

Applied Sciences
Grayscale image processing is a key research area in the field of computer vision and image analysis, where image quality and visualization effects may be seriously damaged by high-density salt and pepper noise.
Ning Cao, Yupu Liu
doaj   +1 more source