Results 41 to 50 of about 59,164,884 (301)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Defence TechnologyTo enhance flow stability and reduce hydrodynamic noise caused by fluctuating pressure, a quasi-periodic elastic support skin composed of flexible walls and elastic support elements is proposed for fluid noise reduction.
Lu Chen +7 more
doaj +1 more source
Reduction of Flicker Phase Noise in High-Speed Photodetectors Under Ultrashort Pulse Illumination
IEEE Photonics Journal, 2021 High-fidelity photodetection enables the transfer of the low noise inherent to optical oscillators to the microwave domain. However, when photodetecting optical signals of the highest timing stability, photodiode flicker (1/f) noise can dominate ...
Dahyeon Lee +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Noise Trading and Market Stability
, 2021 Noise traders are often thought to be detrimental to market stability, increasing volatility and the risk of bubbles and crashes. The effect of noise traders on the learning and development of informed traders, however, has received little attention.
Daniel Ladley (7596332) +1 more
core +2 more sources
Open PhysicsIn this article, we take into consideration the stochastic Schrödinger equation (SSE) perturbed in the Itô sense by the multiplicative Wiener process. We employ an appropriate transformation to turn the SSE into another Schrödinger equation with random ...
Mohammed Wael W., Al-Askar Farah M.
doaj +1 more source
Alexandria Engineering JournalThe stochastic generalized nonlinear Schrödinger equation (SGNLSE) of third order in the Stratonovich sense is examined here. New elliptic, hyperbolic, trigonometric, and rational stochastic solutions are obtained using a modified mapping method. Because
Wael W. Mohammed +3 more
doaj +1 more source
Reduction of magnetic noise limits of orthogonal fluxgate sensor
AIP Advances, 2021 We have further lowered the white noise of an orthogonal fluxgate to about 0.3 pT/√Hz @ 8 Hz. So far, this is the lowest noise reported for a fluxgate magnetometer.
Michal Dressler +2 more
doaj +1 more source