Results 61 to 70 of about 25,813 (128)

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

The FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott, Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor, Friedrich W. Herberg   +6 more
wiley   +1 more source

Macroscopic Market Making Games

Mathematical Finance, EarlyView.
ABSTRACT Building on the macroscopic market making framework as a control problem, this paper investigates its extension to stochastic games. In the context of price competition, each agent is benchmarked against the best quote offered by the others. We begin with the linear case.
Ivan Guo, Shijia Jin
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Ghost effect from Boltzmann theory

Communications on Pure and Applied Mathematics, Volume 79, Issue 3, Page 558-675, March 2026.
Abstract Taking place naturally in a gas subject to a given wall temperature distribution, the “ghost effect” exhibits a rare kinetic effect beyond the prediction of classical fluid theory and Fourier law in such a classical problem in physics. As the Knudsen number ε$\varepsilon$ goes to zero, the finite variation of temperature in the bulk is ...
Raffaele Esposito, Yan Guo, Rossana Marra, Lei Wu   +3 more
wiley   +1 more source

Hyper‐Reduced Model Based on the Proper Orthogonal Decomposition and the LU Factorization Applied to the Neutron Diffusion Eigenvalue Problem

International Journal for Numerical Methods in Engineering, Volume 127, Issue 3, 15 February 2026.
ABSTRACT An efficient method for solving large eigenvalue problems efficiently can be developed using hyper‐reduced order models, such as those arising from the LU Proper Orthogonal Decomposition (LUPOD). The LUPOD employs dominant orthogonal modes along with a flexible number of collocation points to establish a reduced scalar product, thereby ...
A. Vidal‐Ferràndiz, A. Carreño, E. Javaloyas, D. Ginestar, G. Verdú   +4 more
wiley   +1 more source

Peptide and Drug‐Protected Gold Nanoclusters as Promising Biomaterials: Synthesis, Properties, and Applications

Aggregate, Volume 7, Issue 2, February 2026.
The integration of atomically precise gold nanoclusters with peptides or drugs represents a cutting‐edge class of nanomaterials in the biomedical field, owing to their unique physicochemical properties such as water solubility, excellent biocompatibility, low toxicity, and good renal clearance.
Rebeca Garcia Moura, M. Terêsa Machini, Rongchao Jin   +2 more
wiley   +1 more source

Efficient Dynamics: Reduced‐Order Modeling of the Time‐Dependent Schrödinger Equation

Advanced Physics Research, Volume 5, Issue 2, February 2026.
Reduced‐order modeling (ROM) approaches for the time‐dependent Schrödinger equation are investigated, highlighting their ability to simulate quantum dynamics efficiently. Proper Orthogonal Decomposition, Dynamic Mode Decomposition, and Reduced Basis Methods are compared across canonical systems and extended to higher dimensions.
Kolade M. Owolabi
wiley   +1 more source

Characterizing Spatiotemporal Expansion of Pseudomonas aeruginosa Communities in Polymer and Mucin Gel Environments

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 420-435, February 2026.
ABSTRACT Opportunistic colonization and recurring infection by Pseudomonas aeruginosa are substantial risks to lung functionality for people with underlying respiratory diseases such as cystic fibrosis and chronic obstructive pulmonary disease. The complex metabolic and phenotypic adaptations P.
Morgan S. Kim, Glynis L. Kolling, Katharina Ribbeck, Shayn M. Peirce, Jason A. Papin, Roseanne M. Ford   +5 more
wiley   +1 more source

Dimer models and conformal structures

Communications on Pure and Applied Mathematics, Volume 79, Issue 2, Page 340-446, February 2026.
Abstract Dimer models have been the focus of intense research efforts over the last years. Our paper grew out of an effort to develop new methods to study minimizers or the asymptotic height functions of general dimer models and the geometry of their frozen boundaries.
Kari Astala, Erik Duse, István Prause, Xiao Zhong   +3 more
wiley   +1 more source

An Extended Krylov Subspace Method for Decoding Edge‐Based Compressed Images by Homogeneous Diffusion

Numerical Linear Algebra with Applications, Volume 33, Issue 1, February 2026.
ABSTRACT The heat equation is often used to inpaint dropped data in inpainting‐based lossy compression schemes. We propose an alternative way to numerically solve the heat equation by an extended Krylov subspace method. The method is very efficient with respect to the computation of the solution of the heat equation at large times.
Volker Grimm, Kevin Liang
wiley   +1 more source