Results 71 to 80 of about 25,813 (128)
Tutorial on Causal Mediation Analysis for Pharmacometricians
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.ABSTRACT Mediation analyses can support biomarker development by quantifying the part of the total treatment effect on clinical outcome that is mediated by the biomarker. Given that pharmacometricians are often involved in the analysis of biomarker data with pharmacokinetic–pharmacodynamic (PK–PD) models, mediation analysis can be a valuable addition ...
Sebastiaan Camiel Goulooze +2 more
wiley +1 more source
Attractors and upper semicontinuity for an extensible beam with nonlocal structural damping
ZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Volume 106, Issue 2, February 2026.Abstract We analyze the asymptotic behavior of a class of extensible beam models governed by a nonlocal structural damping mechanism of the form φ(El)(−Δ)βut$\varphi (E_l)(-\Delta)^{\beta }u_t$, where β∈λ=(0,1]$\beta \in \lambda =(0,1]$. The coefficient φ$\varphi$ is a degenerate C1$C^{1}$‐function depending on the linear energy El$E_l$ of the system ...
Zayd Hajjej +3 more
wiley +1 more source
Modal Analysis of Water Distribution Systems With the Elastic Water Column Model
Water Resources Research, Volume 62, Issue 2, February 2026.Abstract This paper presents a modal and participation factor (PF) analysis of water distribution systems (WDSs) using the elastic water column model (EWCM). Modal analysis, widely used in other engineering fields, is adapted here to characterize the dynamic behavior of WDSs under transient conditions. By linearizing the EWCM around an operating point,
Morteza Imani +3 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 2, February 2026.The A526V substitution, previously not recognised to affect the functionality of the EAL domain, downregulates the apparent catalytic activity of the PAS‐GGDEF‐EAL ZMO1055 phosphodiesterase and other GGDEF‐EAL proteins. Substitution of A526, which is conserved among homologues, with amino acids with longer aliphatic side chains than valine, reverts to ...
Lian‐Ying Cao +3 more
wiley +1 more source
Strain, Volume 62, Issue 1, February 2026.ABSTRACT Digital image correlation (DIC) is a widely used experimental technique for measuring full‐field deformation, but its application to complex scenarios involving large deformations, discontinuities, or intricate geometries is often hampered by the need for manual region of interest (ROI) definition.
Jeffrey Leu +5 more
wiley +1 more source
International Journal for Numerical Methods in Engineering, Volume 127, Issue 1, 15 January 2026.ABSTRACT Steering a system towards a desired target in a very short amount of time is a challenging task from a computational standpoint. Indeed, the intrinsically iterative nature of optimal control problems requires multiple simulations of the state of the physical system to be controlled. Moreover, the control action needs to be updated whenever the
Matteo Tomasetto +2 more
wiley +1 more source
Generative discovery of partial differential equations by learning from math handbooks. [PDF]
Nat CommunXu H +7 more
europepmc +1 more source
Pan-Cancer Analysis of Cyclic Nucleotide Phosphodiesterases (PDEs) Expression, Variation, and Prognostic Significance. [PDF]
ACS OmegaWu Z, Ren H, Guo F.
europepmc +1 more source
Complex soliton wave patterns of Gross-Pitaevskii systems: application in quantum and optical engineering. [PDF]
Sci RepBilal M +5 more
europepmc +1 more source