Results 111 to 120 of about 120,728,142 (305)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A Theory of Stability in Many-to-many Matching Markets [PDF]
We develop a theory of stability in many-to-many matching markets. We give conditions under which the setwise-stable set, a core-like concept, is nonempty and can be approached through an algorithm. The usual core may be empty.
Federico Echenique, Jorge Oviedo
core
Hurwitz Centenary Conference, Centro Stefano Franscini
, 1996 This book contains the historical development of the seminal paper of Adolf Hurwitz, professor in mathematics at ETH (1892~1919), and its impact on other fields. The major emphasis, however, is on modern results in stability theory and its application in
Jeltsch, Rolf +7 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the stability and control of discrete linear systems with clock synchronization errors
, 2011 This paper considers discrete linear time-invariant systems that can be decomposed into subsystems whose states are synchronized by a common clock whose signal reaches them with delays.
Marek Przedwojski +7 more
core +1 more source
Strong practical stability and stabilization of discrete linear repetitive processes
, 2009 This paper considers two-dimensional (2D) discrete linear systems recursive over the upper right quadrant described by well known state-space models. Included are discrete linear repetitive processes that evolve over subset of this quadrant.
Dabkowski, P +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
An optimal-control based integrated model of supply chain [PDF]
Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
International Journal of Advanced Robotic Systems, 2019 Point stabilization control of a class of asymmetric underactuated high-speed unmanned marine vehicle is discussed, and a robust exponential stabilization control algorithm is proposed based on homogeneous theory, average system theory, and nonlinear ...
Zaopeng Dong +5 more
doaj +1 more source