Results 21 to 30 of about 13,759,341 (300)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
LMI based stability analysis and robust controller design for discrete linear repetitive processes
, 2003 Discrete linear repetitive processes are a distinct class of 2D linear systems with applications in areas ranging from long-wall coal cutting through to iterative learning control schemes.
Owens, D H +6 more
core +2 more sources
Mental models vs cell schemes [PDF]
Investigações em Ensino de Ciências, 2002 Student's mental representations of cell are examined from the perspectives of Johnson-Laird's mental models theory five years after instruction. The observed identity and stability of such representations are then interpreted under the framework of ...
Mª Luz Rodríguez Palmero +1 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Differential Privacy in Federated Learning: An Evolutionary Game Analysis
Applied SciencesThis paper examines federated learning, a decentralized machine learning paradigm, focusing on privacy challenges. We introduce differential privacy mechanisms to protect privacy and quantify their impact on global model performance.
Zhengwei Ni, Qi Zhou
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2019 The notion of Stability [1–3] allows to answer a fundamental question in learning theory: which are the properties that a learning algorithm A should fulfill in order to achieve good generalization performance?
Luca Oneto, Oneto L.
core +1 more source
Lyapunov theory demonstrating a fundamental limit on the speed of systems consolidation
Physical Review ResearchThis article is part of the Physical Review Research collection titled Physics of Neuroscience. The nervous system reorganizes memories from an early site to a late site, a commonly observed feature of learning and memory systems known as systems ...
Alireza Alemi +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
PLoS ONEClassical Chinese poetry is a condensed vessel of Chinese culture, bearing the core ethos of history, philosophy, and ethics. The symbolic imagery system in poetry facilitates the construction of cognitive schemata, thereby advancing transfer learning ...
Dawei Liu, Ping He, Huifen Yan
doaj +1 more source