Results 51 to 60 of about 51,863 (266)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Agroindustrial ScienceThis study evaluated the suspension stability of passion fruit nectar formulated with different concentrations of carboxymethyl cellulose (CMC). Passion fruit nectars with 0, 0.02, 0.1 and 0.2% (w/v) CMC were placed at rest in test tubes at room ...
Jesús Noel-Cuya +3 more
doaj +1 more source
The Electronic Journal of Combinatorics, 2009 Positively weighted graphs have a natural intrinsic metric. We consider finite, positively weighted graphs with a positive lower bound for their minimal weights and show that any two such graphs, which are close enough with respect to the Gromov-Hausdorff metric, are equivalent as graphs.
Bünyamin Demir, Ali Deniz, Sahin Koçak
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Milk ice cream composition and structure improvement [PDF]
Техника и технология пищевых производств, 2018 The work reveals the results of the study devoted to milk ice cream composition improvement in order to meet the requirements for healthy foods (with satisfactory nutritional value) to the fullest extent and to obtain creamy consistency as well as high ...
Tvorogova A. +3 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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The Stability and the Stabilization of Testicular Hyaluronidase
Experimental Biology and Medicine, 1949 Summary1. Testicular hyaluronidase in bulk assaying 150 TRU per mg is stable at room temperature for more than one year.2. Hyaluronidase in concentrated aqueous solution is stable for several months at 10°.C Dilute solutions of the enzyme are less stable.3.
D. R. McCullagh +3 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source