Results 61 to 70 of about 69,372 (313)

Deformations of circle-valued Morse functions on 2-torus

open access: yesPracì Mìžnarodnogo Geometričnogo Centru, 2021
In this paper we give an algebraic description of fundamental groups of orbits of circle-valued Morse functions on T2 with respect to the action of the group of diffeomorphisms of ...
Bohdan Feshchenko
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Social spending and automatic stabilizers in the OECD

open access: yes, 2008
"The macroeconomic literature on automatic stabilization tends to focus on taxes and dismiss the relevance of government expenditure except for unemployment compensation. Our results go sharply contrary to this view. We engage in an empirical analysis of
Jacques Melitz   +5 more
core   +1 more source

The automatic fiscal stabilizers: quietly doing their thing - commentary [PDF]

open access: yes
Fiscal policy ; Consumption (Economics) ; Business cycles ; Economic ...
Olivier Blanchard
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The Stability and the Stabilization of Testicular Hyaluronidase

open access: yesExperimental Biology and Medicine, 1949
Summary1. Testicular hyaluronidase in bulk assaying 150 TRU per mg is stable at room temperature for more than one year.2. Hyaluronidase in concentrated aqueous solution is stable for several months at 10°.C Dilute solutions of the enzyme are less stable.3.
D. R. McCullagh   +3 more
openaire   +2 more sources

On the effectiveness and limits of fiscal stabilizers [PDF]

open access: yes, 2011
The smoothing impact of fiscal stabilizers (proxied by government expenditures) on business cycle volatility is studied for a panel of European Union (EU) countries in the period 1970–1999.
Maria Antoinette Silgoner   +5 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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