Results 71 to 80 of about 30,137 (254)

Systematic NMR analysis of stable isotope labeled metabolite mixtures in plant and animal systems: coarse grained views of metabolic pathways.

PLoS ONE, 2008
BackgroundMetabolic phenotyping has become an important 'bird's-eye-view' technology which can be applied to higher organisms, such as model plant and animal systems in the post-genomics and proteomics era.
Eisuke Chikayama, Michitaka Suto, Takashi Nishihara, Kazuo Shinozaki, Jun Kikuchi   +4 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Isotopically Selected Co‐Doping of 121Sb and 123Sb Pairs in Silicon

Advanced Materials, EarlyView.
Pairs of 121Sb and 123Sb atoms are doped into silicon using single cluster implantation and found to reside substitutionally within the crystal lattice due to self‐annealing with a Sb‐to Sb separation of ≈2 nm. Molecular dynamics simulations reproduce the observed experimental results and single ion cluster detection efficiencies of 94% are ...
Mason Adshead, Maddison Coke, Evan Tillotson, Tomas F Bouvier, Artem Mkrtychyan, Kexue Li, Sam Sullivan‐Allsop, Ricardo Egoavil, William Thornley, Yi Cui, Christopher M. Gourlay, Katie L Moore, Flyura Djurabekova, Sarah J Haigh, Richard J Curry   +14 more
wiley   +1 more source

Multi-Spectroscopic Analysis of Seed Quality and 13C-Stable-Iotopologue Monitoring in Initial Growth Metabolism of Jatropha curcas L.

Metabolites, 2014
In the present study, we applied nuclear magnetic resonance (NMR), as well as near-infrared (NIR) spectroscopy, to Jatropha curcas to fulfill two objectives: (1) to qualitatively examine the seeds stored at different conditions, and (2) to monitor the ...
Takanori Komatsu, Risa Ohishi, Amiu Shino, Kinya Akashi, Jun Kikuchi   +4 more
doaj   +1 more source

Oxygen Evolution Reaction Catalysts for Acidic‐Media CO2 Electrolyzers

Advanced Materials, EarlyView.
Acidic‐media CO2 electroreduction (CO2R) could decarbonize chemical production, despite relying on rare‐earth elements for anodic oxygen evolution reaction (OER). Transferring the learnings from mature sister technologies (water electrolysis) could accelerate technological development.
Mingcheng Huang, Adnan Ozden
wiley   +1 more source

Stable Isotope Tracing Analysis in Cancer Research: Advancements and Challenges in Identifying Dysregulated Cancer Metabolism and Treatment Strategies

Metabolites
Metabolic reprogramming is a hallmark of cancer, driving the development of therapies targeting cancer metabolism. Stable isotope tracing has emerged as a widely adopted tool for monitoring cancer metabolism both in vitro and in vivo.
Dalton Hilovsky, Joshua Hartsell, Jamey D. Young, Xiaojing Liu   +3 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers

Advanced Science, EarlyView.
MitoATP‐nFCM integrates nano‐flow cytometry with fluorogenic probes (ATP/membrane potential) and antibodies to quantify mitochondrial metabolites and protein expression at single‐organelle resolution, exposing oxidative phosphorylation (OXPHOS)‐driven metabolic rewiring in cancers.
Xu Xiao, Cheng Lu, Hao Chen, Jing Zhou, Yunyun Hu, Haonan Di, Guoqiang Su, Xiaomei Yan   +7 more
wiley   +1 more source

Relative Quantitation of Glycopeptides Based on Stable Isotope Labeling Using MALDI-TOF MS

Molecules, 2014
We have developed an effective, sensitive method for quantitative glycopeptide profiling using stable isotope labeling and MALDI-TOF mass spectrometry (MS).
Masaki Kurogochi, Junko Amano
doaj   +1 more source