Results 61 to 70 of about 2,093,866 (195)

Stable isotope dimethyl labelling for quantitative proteomics and beyond [PDF]

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2016
Stable-isotope reductive dimethylation, a cost-effective, simple, robust, reliable and easy-to- multiplex labelling method, is widely applied to quantitative proteomics using liquid chromatography-mass spectrometry. This review focuses on biological applications of stable-isotope dimethyl labelling for a large-scale comparative analysis of protein ...
Jue-Liang, Hsu, Shu-Hui, Chen
openaire   +2 more sources

A ¹⁵N stable isotope semen label to detect mating in the malaria mosquito Anopheles arabiensis Patton [PDF]

, 2008
In previous studies it was determined that the stable isotope 13-carbon can be used as a semen label to detect mating events in the malaria mosquito Anopheles arabiensis. In this paper we describe the use of an additional stable isotope, 15-nitrogen (15N)
Hood Rebecca C, Knols, B.G.J., Gludovacz Doris, Mayr Leo, Gludovacz, D., Knols Bart GJ, Helinski Michelle EH, Helinski, M., Hood-Nowotny, R.C., Mayr, L.   +9 more
core   +1 more source

SIMPEL: using stable isotopes to elucidate dynamics of context specific metabolism

Communications Biology
The capacity to leverage high resolution mass spectrometry (HRMS) with transient isotope labeling experiments is an untapped opportunity to derive insights on context-specific metabolism, that is difficult to assess quantitatively.
Shrikaar Kambhampati, Allen H. Hubbard, Somnath Koley, Javier D. Gomez, Frédéric Marsolais, Bradley S. Evans, Jamey D. Young, Doug K. Allen   +7 more
doaj   +1 more source

Labeling DNA with Stable Isotopes: Economical and Practical Considerations [PDF]

BioTechniques, 2001
Labeling DNA with stable isotopes to measure cell proliferation can be a technique as effective as 3H-thymidine labeling without the limitations imposed by using radioisotopes. Here, we investigated the relative efficiency of four nonradioactive precursors to DNA: [1-13C]-glycine, [1,2-13C2]-glycine, [U-13C]-glucose, and [U-13C, 15N]-thymidine.
G.E. Black, Y.C. Boller, K.A. Kennedy, P. Lecchi, F.P. Abramson   +4 more
openaire   +3 more sources

Synthesis of Stable Isotope Labeled Pefloxacin -D5

Journal of Isotopes
In order to solve the shortage of internal standard reagents for stable isotope labeling of levofloxacin，the synthesis process of stable isotope labeled levofloxacin was studied.
Li ZHANG, Zhongjie XU, Ke FANG
doaj   +1 more source

Review and Prospect of Potential High-resolution Detection Technologies for Ocean Carbon Sequestration

Haiyang Kaifa yu guanli, 2022
In order to promote the accomplishment of the national carbon neutrality goal and enhance the international discourse power in the field of marine carbon sinks, this paper focused on high-resolution methods on the exploration of ocean carbon sink ...
Shijie JING, Fangshuai CHEN, Xin GUO, Xinyue PANG, Zhenzhen HU, Qichao TU, Jihua LIU   +6 more
doaj  

Isotope Labeling Methods for Large Systems

, 2012
A major drawback of nuclear magnetic resonance (NMR) spectroscopy compared to other methods is that the technique has been limited to relatively small molecules.
Patrik Lundström, Annica Theresia Blissing, Blissing, Annica T.,, Alexandra Ahlner, Lundström, Patrik,, Ahlner, Alexandra,   +5 more
core   +1 more source

Advanced Characterization of Environmental Pollutant Metabolism in Human Skin

Journal of Xenobiotics
Ultrafine particles (UFPs) containing polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (BaP), are linked to pollution-induced health concerns, with skin being highly susceptible to contamination.
Rafael Reis, Martine Zanini, Guillaume Lereaux, Ariane Dimitrov, Samia Boudah   +4 more
doaj   +1 more source

Isotope Labeling Methods for Relaxation Measurements

, 2012
Nuclear magnetic spin relaxation has emerged as a powerful technique for probing molecular dynamics. Not only is it possible to use it for determination of time constant(s) for molecular reorientation but it can also be used to characterize internal ...
Patrik Lundström, Annica Theresia Blissing, Blissing, Annica T.,, Alexandra Ahlner, Lundström, Patrik,, Ahlner, Alexandra,   +5 more
core   +1 more source

Hydrogen isotope labeling unravels origin of soil-bound organic contaminant residues in biodegradability testing

Nature Communications
Biodegradability testing in soil helps to identify safe synthetic organic chemicals but is still obscured by the formation of soil-bound ‘non-extractable’ residues (NERs).
Sophie Lennartz, Harriet A. Byrne, Steffen Kümmel, Martin Krauss, Karolina M. Nowak   +4 more
doaj   +1 more source