Results 61 to 70 of about 30,977 (246)

Synthesis of stable isotope–labeled chloroquine and amodiaquine and their metabolites

Journal of Labelled Compounds and Radiopharmaceuticals, 2019
Anti‐malaria drugs chloroquine and amodiaquine and their metabolites were synthesized to incorporate 13C and 15N starting from U‐13C–labeled benzene to give M + 7 isotopomers. Chloroquine and its metabolites were prepared from 7‐chloro‐1,2,3,4‐tetrahydroquinolin‐4‐one through an aryl substitution with the corresponding amines; and the amodiaquine and ...
Ruilian Wu, Robert F. Williams, L.A. “Pete” Silks, Jurgen G. Schmidt   +3 more
openaire   +3 more sources

Labeling DNA with Stable Isotopes: Economical and Practical Considerations [PDF]

BioTechniques, 2001
Labeling DNA with stable isotopes to measure cell proliferation can be a technique as effective as 3H-thymidine labeling without the limitations imposed by using radioisotopes. Here, we investigated the relative efficiency of four nonradioactive precursors to DNA: [1-13C]-glycine, [1,2-13C2]-glycine, [U-13C]-glucose, and [U-13C, 15N]-thymidine.
G.E. Black, Y.C. Boller, K.A. Kennedy, P. Lecchi, F.P. Abramson   +4 more
openaire   +3 more sources

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Stable isotope labelling kinetics of neurofilament light

Brain Communications
Abstract This study provides the first quantification of neurofilament light chain (NfL) kinetics in the human CNS using stable isotope labelling kinetics. NfL is elevated in CSF and blood across a range of traumatic, inflammatory and neurodegenerative diseases of the CNS, and has been increasingly included in clinical trials as a ...
Claire A Leckey, Tatiana A Giovannucci, John B Coulton, Yingxin He, Chihiro Sato, Nupur Ghoshal, Tharini Vignarajah, Zane Jaunmuktane, Nicolas R Barthélemy, Henrik Zetterberg, Donald L Elbert, Kevin Mills, Selina Wray, Randall J Bateman, Ross W Paterson   +14 more
openaire   +2 more sources

Transient Laser‐Shocked Synthesis of Amorphous Layer‐Supported Metal Nanocrystals for Efficient Nitrate Reduction

Advanced Materials, EarlyView.
A general, versatile laser‐shock synthesis process is reported to produce various bimetallic CuNi, CuFe, CuCo, and medium‐entropy CuFeCoNi heterostructures, in which crystalline metal nanoparticles are anchored to amorphous hydroxide supports. During nitrate reduction reaction, the heterostructures undergo dynamic amorphous/crystalline reconstruction ...
Weihua Guo, Jixun Zhang, Siwei Zhang, Yangbo Ma, Yun Song, Jianjun Su, Zihao Li, Yinger Xin, Qiang Zhang, Mingming He, Ruixuan Wang, Rui Xue, Shibo Xi, Ying Wang, Shenlong Zhao, Tao Yang, Zhengxiao Guo, Ben Zhong Tang, Ruquan Ye   +18 more
wiley   +1 more source

Advanced Characterization of Environmental Pollutant Metabolism in Human Skin

Journal of Xenobiotics
Ultrafine particles (UFPs) containing polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (BaP), are linked to pollution-induced health concerns, with skin being highly susceptible to contamination.
Rafael Reis, Martine Zanini, Guillaume Lereaux, Ariane Dimitrov, Samia Boudah   +4 more
doaj   +1 more source

Review and Prospect of Potential High-resolution Detection Technologies for Ocean Carbon Sequestration

Haiyang Kaifa yu guanli, 2022
In order to promote the accomplishment of the national carbon neutrality goal and enhance the international discourse power in the field of marine carbon sinks, this paper focused on high-resolution methods on the exploration of ocean carbon sink ...
Shijie JING, Fangshuai CHEN, Xin GUO, Xinyue PANG, Zhenzhen HU, Qichao TU, Jihua LIU   +6 more
doaj  

Enhanced Photocatalytic H2O2 Production on Terpyridine‐Based Acrylonitrile‐Linked Covalent Organic Frameworks with Asymmetric Localized Electron Distribution

Advanced Materials, EarlyView.
Asymmetric localized electron distribution has been optimized in covalent organic frameworks to enhance *O2 adsorption and facilitate charge transfer, boosting photocatalytic two‐electron transfer oxygen reduction toward H2O2 production from water and air.
Qinglan Zhao, Mengmeng Ce, Hengtao Lei, Tianyun Jin, Zhipeng Xie, Yushen Liu, Shengyi Yang, Xinwen Ou, Mohammad Farhadpour, Song‐Zhu Kure‐Chu, Xuan‐He Liu, Liang Zhang, Jimmy C. Yu   +12 more
wiley   +1 more source

Synthesis of Stable Isotope Labeled Pefloxacin -D5

Journal of Isotopes
In order to solve the shortage of internal standard reagents for stable isotope labeling of levofloxacin，the synthesis process of stable isotope labeled levofloxacin was studied.
Li ZHANG, Zhongjie XU, Ke FANG
doaj   +1 more source

Bias‐Triggered Conductivity Relaxation (BCR): A Unique Tool to Simultaneously Investigate Thermodynamics, Kinetics, and Electrostatic Effects of Oxygen Reactions in MIEC Thin Films

Advanced Materials, EarlyView.
This work develops bias‐triggered conductivity relaxation as a novel technique to study oxygen reactions in mixed ionic‐electronic conducting thin films by integrating electrochemical titration and electrical conductivity relaxation to achieve synchronous multi‐parameter characterization, providing simultaneous electronic, ionic, and extraordinarily ...
Alexander Stangl, Alexander Schmid, Adeel Riaz, Jürgen Fleig, Arnaud Badel   +4 more
wiley   +1 more source