Identification of diverse antibiotic resistant bacteria in agricultural soil with H218O stable isotope probing combined with high-throughput sequencing. [PDF]
Hernández M +3 more
europepmc +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Discovery of lignin-transforming bacteria and enzymes in thermophilic environments using stable isotope probing. [PDF]
Levy-Booth DJ +7 more
europepmc +1 more source
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao +6 more
wiley +1 more source
DNA stable isotope probing on soil treated by plant biostimulation and flooding revealed the bacterial communities involved in PCB degradation. [PDF]
Vergani L +6 more
europepmc +1 more source
Atomically correlated phosphorus–sulphur sites are introduced into graphitic carbon nitride to regulate charge distribution, suppress localized trapping, and enhance oxygen activation. The resulting metal‐free photocatalyst selectively promotes the two‐electron oxygen reduction pathway, enabling efficient hydrogen peroxide production in pure water ...
Adnan Ahmad +12 more
wiley +1 more source
Anammox bacterial abundance and diversity in different temperatures of purple paddy soils by 13C-DNA stable-isotope probing combined with high-throughput sequencing. [PDF]
Yu Z +6 more
europepmc +1 more source
Through quantitative ligand stripping of [Cu18H17(PR3)10]+ nanoclusters via intramolecular interaction modulation, selectivity for CO2 electroreduction to C2H4 is significantly enhanced. The weakly coordinating ligand triggers dual‐ligand stripping (FEC2H4 = 70.59%), whereas the strongly coordinating ligand results in single‐ligand retention (FEC2H4 ...
Ziqi Chen +8 more
wiley +1 more source
Diversity of novel archaeal viruses infecting methanogens discovered through coupling of stable isotope probing and metagenomics. [PDF]
Ngo VQH +9 more
europepmc +1 more source

