Results 71 to 80 of about 236,951 (263)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Distortion of Stable Matching
CoRRWe initiate the study of distortion in stable matching. Concretely, we aim to design algorithms that have limited access to the agents' cardinal preferences and compute stable matchings of high quality with respect to some aggregate objective, e.g., the social welfare.
Aris Filos-Ratsikas +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Stable Matching with Evolving Preferences
CoRR, 2015 We consider the problem of stable matching with dynamic preference lists. At each time step, the preference list of some player may change by swapping random adjacent members. The goal of a central agency (algorithm) is to maintain an approximately stable matching (in terms of number of blocking pairs) at all times.
Varun Kanade +2 more
openaire +5 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
World Electric Vehicle JournalElectric-powered vehicles (EVs) allow for an environmentally friendly and economic alternative to fuel-running ones. However, such an alternative is expected to impose further usage hikes and periods of instability on cities’ power systems.
Ahmad Nahar Quttoum +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
D2D data collaboration forwarding mechanism based on contract theory
Dianxin kexue, 2018 A contract theory-based D2D data forwarding mechanism was proposed for device-to-device (D2D) communications under cellular networks.Firstly,considering the selfishness of users,a model of principal-agent was constructed,which regarded the transmitter ...
Jin ZHOU, Luyang ZHANG, Peng YANG
doaj
UAV Network Channel Allocation Method Based on Bipartite Graph Popular Matching Algorithm
IEEE AccessTo address the challenges of selecting task schemes and ensuring secure channels duringdata collection and transmission by unmanned aerial vehicles, the study divides the secure transmission model into physical domain and social domain based on graph ...
Weihan Li, Jianwei Guo
doaj +1 more source