Results 91 to 100 of about 779,888 (355)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Enhancing Transportation Efficiency with Optimal Container Placement Using the Bat Algorithm
Transport and TelecommunicationThe objective of this article is to provide an in-depth exploration of the complex task of container storage at seaports, a problem characterized as one of the challenging NP (Non-Deterministic Polynomial time) problems.
Khadidja Yachba +2 more
doaj +1 more source
Numerical computation for parallel plate thermoacoustic heat exchangers in standing wave oscillatory flow [PDF]
, 2011 A simplified computational method for studying the heat transfer characteristics of parallel plate thermoacoustic heat exchangers is presented. The model integrates the thermoacoustic equations of the standard linear theory into an energy balance-based ...
Piccolo, Antonio, A. Piccolo
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Cost Analysis of Direct Methanol Fuel Cell Stacks for Mass Production
Energies, 2016 Fuel cells are very promising technologies for efficient electrical energy generation. The development of enhanced system components and new engineering solutions is fundamental for the large-scale deployment of these devices.
Mauro Francesco Sgroi +9 more
doaj +1 more source
A Late Pleistocene sea level stack
, 2014 . Late Pleistocene sea level has been reconstructed from ocean sediment core data using a wide variety of proxies and models. However, the accuracy of individual reconstructions is limited by measurement error, local variations in salinity and ...
R. Spratt, L. Lisiecki
semanticscholar +1 more source
Standardized Protocol Stack for the Internet of (Important) Things
IEEE Communications Surveys and Tutorials, 2013 We have witnessed the Fixed Internet emerging with virtually every computer being connected today; we are currently witnessing the emergence of the Mobile Internet with the exponential explosion of smart phones, tablets and net-books.
M. Palattella +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 1941 Date:1941Ella Stack and her family moved to Darwin in 1961. She was first employed for a few weeks mid-1961 by a local GP and then in 1962, Ella took over as long-term locum. She was one of two private practitioners in Darwin. Cyclone Tracy hit Darwin in
Stack, Ellen Mary
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