Results 71 to 80 of about 178,274 (267)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Numerical Analysis of Flow in U-Type Solid Oxide Fuel Cell Stacks

Energies
Numerical analysis of a U-type solid oxide fuel cell stack was performed using computational fluid dynamics to investigate the effects of stack capacities and fuel/air utilization rates on the internal flow uniformity.
Hao Yuan Yin, Kun Woo Yi, Young Jin Kim, Hyeon Jin Kim, Kyong Sik Yun, Ji Haeng Yu   +5 more
doaj   +1 more source

Scientific Opinion on application (EFSA‐GMO‐NL‐2012‐108) for the placing on the market of the herbicide‐tolerant genetically modified soybean MON 87708 × MON 89788 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Monsanto

EFSA Journal, 2015
Single events MON 87708 and MON 89788 were combined to produce the stack two‐event soybean MON 87708 × MON 89788. The EFSA GMO Panel previously assessed the two single events and did not identify safety concerns in the context of their scope. No new data
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source

PENGARUH PANJANG STACK SELUBUNG KABEL TERHADAP PERUBAHAN SUHU PADA SISTEM PENDINGIN TERMOAKUSTIK

Spektra: Jurnal Fisika dan Aplikasinya, 2017
Research on environmentally friendly thermo-acoustic coolants uses a heat exchanger from the cable sheath material. The resonator tube used in the thermoelectric cooler is a 5.25 cm diameter PVC (polyvinyl chloride) tube with a length of 87 cm ...
Indah Kharismawati, Hanif Rafika Putri
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Hidden Abstract Stack Markov Models with Learning Process

Mathematics
We present hidden abstract stack Markov models (HASMMs) with their learning process. The HASMMs we offer carry the more expressive nature of probabilistic context-free grammars (PCFGs) while allowing faster parameter fitting of hidden Markov models (HMMs)
Mete Özbaltan
doaj   +1 more source

Digital Infrastructure, Liminality, and World-Making Via Asia| Gateways, Sieves and Domes: On the Infrastructural Topology of the Chinese Stack

International Journal of Communication, 2021
This article proposes a topological model capable of accounting for the scale and complexity of China’s digital infrastructure. Beginning with the troubled development of a submarine data cable between Los Angeles and Hong Kong, it identifies the ...
Gabriele de Seta
doaj