Results 61 to 70 of about 779,888 (355)

Place-based innovation for sustainable and resilient human systems

open access: yesSustainable Earth Reviews
This paper critically examines fail-fast culture and its compatibility with fragile contexts. It argues that to address complex global challenges, a nuanced ‘fail well’ approach is required. Drawing on the Gothenburg innovation ecosystem—among others—the
Björn Rust, Sascha Rust
doaj   +1 more source

Detect Windows Code Injection by Cross-validating Stack and VAD Information

open access: yesJournal of Harbin University of Science and Technology
Windows 32/64-bit code injection attacks are a common attack technique by malware. In the field of memory forensics, the existing code injection attack detection technologies cannot handle dynamic content in terms of verification integrity, and cannot be
ZHAI Jiqiang   +4 more
doaj   +1 more source

Are Code Examples on an Online Q&A Forum Reliable?: A Study of API Misuse on Stack Overflow

open access: yesInternational Conference on Software Engineering, 2018
Programmers often consult an online Q&A forum such as Stack Overflow to learn new APIs. This paper presents an empirical study on the prevalence and severity of API misuse on Stack Overflow.
Tianyi Zhang   +4 more
semanticscholar   +1 more source

The Hilbert stack

open access: yesAdvances in Mathematics, 2014
Let π: X -> S be a morphism of algebraic stacks that is locally of finite presentation with affine stabilizers. We prove that there is an algebraic S-stack, the Hilbert stack, parameterizing proper algebraic stacks mapping quasi-finitely to X. This was previously unknown, even for a morphism of schemes.
Hall, Jack, Rydh, David
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Technology and equipment of vertical‑stack molding for the production of castings without pattern drafts

open access: yesЛитьë и металлургия, 2021
The article reports on the new technology and equipment of vertical‑stack molding (VSM), created by OJSC “BELNIILIT” for the manufacture of vertical‑stack molds.
V. V. Fonov   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Acetylcholinesterase enzyme among cancer patients a potential diagnostic and prognostic indicator a multicenter case–control study

open access: yesScientific Reports
Acetylcholinesterase enzyme (AChE) activity is impaired by a variety of inhibitors including organophosphorus pesticides, leading to the accumulation of acetylcholine.
Gasmelseed Y. Ahmed   +2 more
doaj   +1 more source

Scientific Opinion on an application (EFSA‐GMO‐NL‐2010‐80) for the placing on the market of herbicide‐tolerant genetically modified maize NK603 × T25 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Monsanto

open access: yesEFSA Journal, 2015
Single events NK603 and T25 were combined to produce the stack two‐event maize NK603 × T25. The EFSA GMO Panel previously assessed the two single events and did not identify safety concerns in the context of their scope.
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source

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