Results 81 to 90 of about 178,274 (267)
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
The Journal of Symbolic Logic, 2009 AbstractWe show that either of the following hypotheses imply that there is an inner model with a proper class of strong cardinals and a proper class of Woodin cardinals. 1) There is a countably closed cardinal κ ≥ ℵ such that □κ and □(κ) fail. 2) There is a cardinal κ such that κ is weakly compact in the generic extension by Col(κ, κ+).
Ronald Jensen +3 more
openaire +3 more sources
The Influence of Building Airtightness on Airflow in Stairwells
Buildings, 2019 Airflow into stairwells due to stack effect is a concern affecting fire safety, energy performance, and indoor air quality. Stack effect in tall buildings can create significant pressure differentials in vertical shafts when differences in outdoor and ...
Philip Mckeen, Zaiyi Liao
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Iranian South Medical Journal, 2019 Background: In developing countries, air pollution caused by industries constitutes a serious threat to public health. The present study was conducted to determine the dispersion patern and assess the health risks of PM10 emitted from the stacks of a ...
Saeid Shojaee Barjoee +4 more
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song +10 more
wiley +1 more source
Application of Hardware Encryption while Operating with STACK for Exploit Safeguard
Безопасность информационных технологий, 2011 This paper deals with stack data unauthorized modification protection methods by means of data encryption while fulfilling direct or indirect commands PUSH and POP. These methods are aimed at counteraction of exploits, which substitute return address and
D. V. Gurov
doaj