Results 181 to 190 of about 15,788 (294)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Student perspectives on AI‐supported formative assessment in pharmacology

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims High‐quality feedback is crucial for helping medical students understand and apply core concepts of pharmacology, yet personalized feedback is resource‐intensive to produce. Artificial intelligence (AI) offers a potential solution, but little is known about students' perspectives on AI‐generated feedback.
Jon Andsnes Berg   +6 more
wiley   +1 more source

Assessing the impact of socioeconomic determinants and management models on primary health care in Catalonia. [PDF]

open access: yesAten Primaria
Manzanera R   +5 more
europepmc   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval   +6 more
wiley   +1 more source

A customised scale for measuring retail service quality in a college shop: a context specific approach

open access: yes
The purpose of this research was to modify an existing scale to measure retail service quality in a college shop. This scale was modified based on the retail service quality scale (RSQS) to make it more contexts specific and culturally sensitive for the ...
Yaghi, Derar
core  

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé   +12 more
wiley   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa   +21 more
wiley   +1 more source

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