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CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Context: The impacts of Covid-19 pandemic conditions in Canada’s long-term residential care (LTRC) sector have demonstrated that future pandemic preparedness necessitates not only recovery but deeper sectoral transformation of longstanding ...
Nick Boettcher+2 more
doaj +1 more source
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
Desain dan Implementasi Face Recognition dan Live Streaming pada Sistem Digital Assistant untuk Staf Medik Fungsional menggunakan Google Glass [PDF]
DIANE is a digital assistant system that aims to fasten the doctor access to various informations at the hospital such as health care facility, medical records, and also human resource data. The fasten access could be achieved by implementing face recognition and live streaming as part of the digital assistant system.
arxiv +1 more source
Workload forecasting for a call center: Methodology and a case study [PDF]
Today's call center managers face multiple operational decision-making tasks. One of the most common is determining the weekly staffing levels to ensure customer satisfaction and meeting their needs while minimizing service costs. An initial step for producing the weekly schedule is forecasting the future system loads which involves predicting both ...
arxiv +1 more source
Pierre SANTUCCI is a principal investigator at the CNRS—Aix Marseille Université and recipient of a FEBS Excellence Award. He was also recently appointed FEBS Open Bio Publishing Liaison Officer. In this Open Chat with…, he discusses the importance of engaging with scientific societies and their journals, and highlights through some of his personal ...
Pierre Santucci, Ioannis Tsagakis
wiley +1 more source
ANALISIS PELAKSANAAN MUTASI KEPEGAWAIAN OLEH KEPALA DAERAH DI KABUPATEN MAJENE
The main problem of this research is the Analysis of the Implementation of Staff Movements by the Regional Heads in Majene Regency.The method in this study is descriptive qualitative, which provides an objective description of ...
Rahmat Andika+2 more
doaj +1 more source
Identifying Components of Staffing System to Develop Administrative Integrity [PDF]
Objective: Administrative integrity and efficiency are two factors that can play a major role in the development of a country. This is mainly due to the fact that administrative systems could be used to regulate activities in order to achieve specific ...
Hossein Imani+3 more
doaj +1 more source
The ways of preventing drug use by military personnel of military organizations [PDF]
• Currently, drug addiction and drug use as one of the most serious social challenges in our country are the cause of many injuries and deviations, and employees working in military organizations as part of Society is naturally exposed to the tendency to
javad abdi
doaj