Results 41 to 50 of about 44,292 (263)

RNA sequencing of the human milk fat layer transcriptome reveals distinct gene expression profiles at three stages of lactation. [PDF]

PLoS ONE, 2013
Aware of the important benefits of human milk, most U.S. women initiate breastfeeding but difficulties with milk supply lead some to quit earlier than intended.
Danielle G Lemay, Olivia A Ballard, Maria A Hughes, Ardythe L Morrow, Nelson D Horseman, Laurie A Nommsen-Rivers   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The influence of ordinal number and stage of lactation on milkability traits in Holstein cows

Mljekarstvo, 2013
Milkability traits have an increasing importance in modern cattle production, although they are the secondary selective trait. The machine milking of cows has indicated that there is no complete alignment between the machine and the animals, what lead to
Pero Mijić, Tina Bobić, Maja Gregić, Zdenko Ivkić, Mirjana Baban   +4 more
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

The human milk microbiome aligns with lactation stage and not birth mode

Scientific Reports, 2022
AbstractWe analysed the human milk microbiome in a cohort of 80 lactating women and followed the dynamics in taxa over the course of lactation from birth to 6 months. Two hundred and thirty one milk samples were collected from full-term lactating women at 1, 4, 8 and 24 weeks following birth and analysed for microbiota composition using 16S rRNA ...
Lyons, Katriona E, Shea, Carol-Anne O ', Grimaud, Ghjuvan, Ryan, C Anthony, Dempsey, Eugene, Kelly, Alan L, Ross, R Paul, Stanton, Catherine   +7 more
openaire   +4 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Non-genetic factors of udder morphology traits in Istrian ewes

Mljekarstvo, 2013
Considering the facts that Istrian sheep is Croatian indigenous breed with the highest milk production, and increasing interest of local farmers for machine milking implementation, the aim of this study was to determine the factors affecting udder ...
Valentino Držaić, Ivan Vnučec, Boro Mioč, Zvonimir Prpić, Vesna Pavić   +4 more
doaj  

Composition, cellularity and biochemical profile of milk from primiparous and pluriparous Holstein cows during the stages of lactation [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The aim of the study was to verify the influence of calving order and stage of lactation on milk composition, SCC and biochemical profile of whey from Holstein cows.
D.D. Alves, D.G. Silva, G.A. Aguiar, G.S. Nogueira, M.F. Silva, R.V.R.S. Leite, J.C. Lacerda-Neto   +6 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source