Results 51 to 60 of about 1,458,489 (296)
Limitations of Machine Translation
Armenian Folia Anglistika, 2010 Along with technological advancements worldwide there is a growing demand in machine translation as well. With its various and most diverse translation opportunities, computer translation, however, has its disadvantages and restrictions.
Gayane Shmavonyan
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Bio-ProtocolThe Plasmodium parasites that cause malaria undergo an obligate, asymptomatic developmental stage in the host liver before initiating the symptomatic blood-stage infection.
James McLellan +2 more
doaj +1 more source
Między Oryginałem a Przekładem, 2019 Contemporary Conceptualisations of Translation Activity Proposed by Representatives of French Translation Enterprises In this article, we examine to what extent the traditional conceptualisation of translation activity, i.e.
Anna Kuźnik
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
An analysis of manga translated from Japanese to Russian: based on descriptive translation studies
Әл-Фараби Атындағы Қазақ Ұлттық Университеті хабаршы шығыстану сериясы, 2020 The purpose of this study is to analyze the Japanese version and the two Russian versions of the Japanese Manga written by Nakazawa Keiji, Hadashi no Gen (Barefoot Gen), based on Descriptive Translation Studies, and find out tendencies of the ...
Ниномия Т.
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Performing Translation as Practice-led Research: The Case of Carr’s “By the Bog of Cats…” in Brazil
Aletria: Revista de Estudos de Literatura, 2015 This article offers a retrospective analysis of aspects of my translation for the stage of Marina Carr’s By the Bog of Cats… into Brazilian Portuguese.
Alinne Balduino P. Fernandes
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source