Results 41 to 50 of about 1,458,489 (296)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Translation Studies Perspective to the Stage Adaptations of the Novel Beş Sevim Apartmanı by Mine Söğüt

open access: yesTiyatro Eleştirmenliği ve Dramaturji Bölümü Dergisi, 2022
Mine Söğüt is known for her debut novel, Beş Sevim Apartmanı, a work in which the author’s experimental technique on the theme of belief adds a literary value to the expression of psychological issues.
Naciye Sağlam
doaj   +1 more source

Low-resource machine translation using MATREX: The DCU machine translation system for IWSLT 2009 [PDF]

open access: yes, 2009
In this paper, we give a description of the Machine Translation (MT) system developed at DCU that was used for our fourth participation in the evaluation campaign of the International Workshop on Spoken Language Translation (IWSLT 2009).
Cetinoglu, Ozlem   +4 more
core   +2 more sources

Pharmacology and clinical drug candidates in redox medicine [PDF]

open access: yes, 2015
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I   +11 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

La traduction comme négociation entre traducteur et éditeur

open access: yesMiędzy Oryginałem a Przekładem, 2017
Translation as a Negotiation Between Translator and Publisher: Example of the Dystopian Trilogy Méto and Its Polish Translation In the present study, taking the example Yves Grevet’s dystopian trilogy for youth Méto and its Polish translation, we ...
Natalia Paprocka, Paweł Łapiński
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Small studies, big decisions: the role of pilot/feasibility studies in incremental science and premature scale-up of behavioral interventions

open access: yesPilot and Feasibility Studies, 2021
Background Careful consideration and planning are required to establish “sufficient” evidence to ensure an investment in a larger, more well-powered behavioral intervention trial is worthwhile.
Michael W. Beets   +4 more
doaj   +1 more source

The sweetheart factor: Tracing translation in Martin Crimp’s writing for theatre [PDF]

open access: yes, 2016
Martin Crimp’s activity as a playwright includes the translation and adaptation of the theatrical works of other writers. This article considers how Crimp’s theoretical and practical engagement with translation is manifested in his writing for the stage.
Brodie, G
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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