Results 81 to 90 of about 3,560,535 (403)
Aims: Several artificial bone grafts have been developed but fail to achieve anticipated osteogenesis due to their insufficient neovascularization capacity and periosteum support. This study aimed to develop a vascularized bone-periosteum construct (VBPC)
Tsai-Sheng Fu+5 more
doaj +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts [PDF]
Previous observations of association of mRNAs and ribosomes with subcellular structures highlight the importance of localised translation. However, little is known regarding associations between eukaryotic translation initiation factors and cellular ...
Barbarese+82 more
core +1 more source
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Whitaker, W., McNeill, Bedford
openaire +2 more sources
Some people have red urine and faeces after eating beetroot, but how much do we know about beetroot's ability to intensify the colour of blood, thereby making blood stains impossible to remove? One summer evening in 2004 our 11 year old son went to bed after various delaying tactics—arguments about friends who stay up later, forgetting to brush teeth,
Julia Handysides, Stuart Handysides
openaire +3 more sources
Platinum blue staining of cells grown in electrospun scaffolds
Fibroblast cells grown in electrospun polymer scaffolds were stained with platinum blue, a heavy metal stain, and imaged using scanning electron microscopy. Good contrast on the cells was achieved compared with samples that were gold sputter coated.
Mohammed Yusuf+6 more
doaj +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Surface properties and susceptibility to staining of a resin composite after brushing with different whitening toothpastes [PDF]
Objectives This study investigated the effects of different whitening toothpaste (WT) on the surface properties and staining susceptibility of a resin composite.
Aline da Silva Barros+4 more
doaj +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
Sequential epiretinal membrane removal with internal limiting membrane peeling in brilliant blue G-assisted macular surgery [PDF]
Purpose To assess the selectivity of brilliant blue G (BBG) staining by analysing the morphological components of unstained and stained tissue obtained during epiretinal membrane (ERM) removal with internal limiting membrane (ILM) peeling in BBG ...
Eibl, Kirsten H.+5 more
core +3 more sources