Results 101 to 110 of about 2,777,639 (313)

Cry2 prompts clock oscillation and temporomandibular joint homeostasis under mechanical loading

Bone & Joint Research
Aims: Cartilage metabolism exhibits circadian rhythms (CR), and disruption of these often correlates with cartilage degeneration. Mechanical stimulation is a vital zeitgeber of CR in cartilage.
Chenzhi Li, Yujie Zhao, Jing Song, Nan Wang, Xiangyan Zhang, Mao Sui, Xuemin Zeng, Xiao Yuan, Dapeng Ren   +8 more
doaj   +1 more source

The time-dependent expression of keratins 5 and 13 during the reepithelialization of human skin wounds [PDF]

, 1993
The time-dependent reepithelialization of 55 human surgical skin wounds with a wound age between 8h and more than 2 months was investigated by the immunohistochemical localization of cytokeratins 5 and 13.
A. Nerlich, D Cooper, D Cooper, D Mischke, EJ O'Keefe, G Gabbiani, GD Winter, GNP Muijen van, J-P Ortonne, J. Tübel, JL Cordell, JN Mansbridge, LJ Ordman, M Guo, P Betz, P. Betz, R Moll, R Moll, R. Penning, RAF Clark, SC Pang, SM Hsu, SV Pollack, TT Sun, W Oehlert, W. Eisenmenger   +25 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The staining potential of the dental enamel with cerium oxide nanoparticle mouthwash and Glycyrrhiza glabra nanoparticle mouthwash: An in vitro study

Journal of Indian Society of Periodontology
Background: This study aims to formulate and evaluate the staining effect of three different types of mouthwash containing nanoparticles (NPs) and compare them with chlorhexidine (CHX) mouthwash on dental enamel.
M. A. Lavanya, H. Esther Nalini, S. R. Bharathi, S. Tamil Selvi, S. Nivethitha, S. Reshma   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Vascular remodelling and fibrotic changes in the joint capsule during periprosthetic knee infections

Bone & Joint Research
Aims: Periprosthetic joint infection (PJI) represents one of the most severe complications following joint arthroplasty, often associated with a high recurrence rate despite appropriate therapeutic interventions. The underlying mechanisms contributing to
Renqiu Qiao, Julia Mehl, Bo Qi, Ellen Sistemich, Wei Fan, Stephanie Kirschbaum, Stefanie Donner, Mario Thiele, Denise Jahn, Clemens Gwinner, Georg Duda, Carsten F. Perka, Arne Kienzle   +12 more
doaj   +1 more source

Association of p60c-src with endosomal membranes in mammalian fibroblasts. [PDF]

, 1992
We have examined the subcellular localization of p60c-src in mammalian fibroblasts. Analysis of indirect immunofluorescence by three-dimensional optical sectioning microscopy revealed a granular cytoplasmic staining that co-localized with the microtubule
Kaplan, KB, Morgan, DO, Swedlow, JR, Varmus, HE   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Comparative Evaluation of Beverage-Induced Surface Alterations on Dental Enamel: An In Vitro Biomaterial Study

Bioengineering
Background/Objectives: Despite advances in preventive dental care, tooth enamel erosion remains a relevant concern, and very few comparisons of surface topography have been carried out under controlled conditions in the laboratory.
Ioana Elena Lile, Otilia Stana, Diana Marian, Carolina Cojocariu, Luminiţa Ligia Vaida, Anda Olivia Jesamine Samoilă, Iustin Olariu   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source