Results 151 to 160 of about 2,201,246 (301)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
An efficient error resilience scheme based on wyner-ziv coding for region-of-Interest protection of wavelet based video transmission [PDF]
, 2008 In this paper, we propose a bandwidth efficient error resilience scheme for wavelet based video transmission over wireless channel by introducing an additional Wyner-Ziv (WZ) stream to protect region of interest (ROI) in a frame.
Zhuo, X, Loo, KK, Cosmas, J, Yip, PY
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The use of pseudo-multivariate standard error to improve the sampling design of coral monitoring programs. [PDF]
PeerJ, 2020 Montilla LM +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Superconvergence and error estimation of finite element solutions to fire-exposed frame problems [PDF]
, 2000 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.When a fire reaches the point of flashover the hot gases inside the burning room ignite resulting in furnace-like conditions.
Kirby, James Alexander, Kirby, J.A.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Space-time decision feedback equalisation using a minimum bit error rate design for single-input multi-output channels [PDF]
, 2007 This contribution proposes a minimum bit error rate (MBER) decision feedback equaliser (DFE) designed for single-input multiple-output (SIMO) systems employing a quadrature phase shift keying (QPSK) modulation scheme. It is shown that this MBER design is
Shi, Y. +3 more
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source