Results 141 to 150 of about 2,201,246 (301)
A Standard-Compatible Forward Error Correction Extension for the Automatic Identification System
Journal of Marine Science and EngineeringThe Automatic Identification System (AIS) is a maritime radio system that regularly broadcasts vessel data, such as the vessel’s identification, position, course and speed.
Armin Dammann +3 more
doaj +1 more source
Comparison of small-sample standard-error corrections for generalised estimating equations in stepped wedge cluster randomised trials with a binary outcome: A simulation study. [PDF]
Stat Methods Med Res, 2021 Thompson JA +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Continuity Correction and Standard Error Calculation for Testing in Proportional Hazards Models
StatsStandard asymptotic inference for proportional hazards models is conventionally performed by calculating a standard error for the estimate and comparing the estimate divided by the standard error to a standard normal distribution.
Daniel Baumgartner, John E. Kolassa
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Evaluation of balance measurement uncertainty based on standard error of calibration coefficients
Kongqi donglixue xuebaoThe measurement uncertainty of strain gauge balance is one of the important sources of uncertainty in aircraft wind tunnel test data. The conventional methodology obtains the balance calibration formula through the comprehensive loading residual method ...
Chao Wang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Bootstrap for estimating the mean squared error of the spatial EBLUP [PDF]
This work assumes that the small area quantities of interest follow a Fay-Herriot model with spatially correlated random area effects. Under this model, parametric and nonparametric bootstrap procedures are proposed for estimating the mean squared error ...
Isabel Molina +2 more
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source