Results 121 to 130 of about 7,349,903 (259)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Note on the radical inflation in the estimates of error variance in measurement models
Frontiers in EducationThis note discusses the radical technical inflation in error variance and the related standard error of test scores from both conceptual and empirical viewpoints. This technical inflation arises as a direct consequence of the technical underestimation of
Jari Metsämuuronen, Jari Metsämuuronen
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Application of Different Standard Error Estimates in Reliable Change Methods. [PDF]
Arch Clin Neuropsychol, 2021 Hammers DB, Duff K.
europepmc +1 more source
, 2016 Distribution derived values to assign change: 0.5 standard deviation (SD) and Standard Error of Measurement (SEM).
Lesley K. Fellows (589149) +5 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Error distance of standard Reed-Solomon codes
四川大学学报. 自然科学版, 2017 Error distance plays an important role in the decoding of standard Reed-Solomon codes. In 2012, Hong and Wu proposed a famous conjecture of standard Reed-Solomon codes on error distance.
SONG Qing-Shan +2 more
doaj
Average Measurement Error and Standard Error for 0.05% and 0.5% Chlorine Solutions.
, 2016 Dashed lines represent 10% acceptable margin of measurement error. Error bars represent standard error.
Daniele Lantagne (1813255) +3 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source