Results 101 to 110 of about 7,349,903 (259)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Mean of the task duration (T) for the four conditions with error bars representing standard error.
Mean of the task duration (T) for the four conditions with error bars representing standard error.
Andrea Clerico (497324) +3 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The two-parameter logistic (2PL) item response theory model is a statistical model for analyzing multivariate binary data. In this article, two groups are brought onto a common metric using the 2PL model using linking methods. The linking methods of mean–
Alexander Robitzsch
doaj +1 more source
Standard errors: A review and evaluation of standard error estimators using Monte Carlo simulations [PDF]
Characteristics of a population are often unknown. To estimate such characteristics, random sampling must be used. Sampling is the process by which a subgroup of a population is examined in order to infer the values of the population'
Bradley Harding +2 more
doaj
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Standard income tax service ..
Issue for 1915 includes the 2nd enl. ed. of the company's Status of bonds under the Federal income tax.Issues for 1921- published in 2 sections.Issues for 1915-1920 published annually.
Standard and Poor's Corporation. +1 more
core

