Results 111 to 120 of about 2,201,246 (301)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Adaptive near minimum error rate training for neural networks with application to multiuser detection in CDMA communication systems [PDF]

open access: yes, 2005
Adaptive training of neural networks is typically done using some stochastic gradient algorithm that tries to minimize the mean square error (MSE). For many applications, such as channel equalization and code-division multiple-access (CDMA) multiuser ...
Hanzo, L., Chen, S., Samingan, A.K.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Standard Error of Sample Means [PDF]

open access: yes, 1998
This page, created by Richard Lowry of Vassar College, calculates the standard error of a sampling distribution of sample means when users input the mean and standard deviation of the population and the sample size.
Lowry, Richard
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Mean relative error and standard relative deviation [PDF]

open access: yes
Statistics on the natural log scale, such as differences, regression coefficients, and standard deviations, frequently arise when analyzing log‐transformed data or modeling binary, count, or time‐to‐event data.
Chatfield, Mark D.   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Estimation of standard error of the parameter of change using simulations [PDF]

open access: yesRevista Română de Statistică, 2015
The main objective of this paper is to present the procedure for estimating standard error of parameter of change (index) of turnover in R software (R core team, 2014) when samples are coordinated.
Djordje Petkovic
doaj  

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