Results 131 to 140 of about 2,201,246 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Error distance of standard Reed-Solomon codes
四川大学学报. 自然科学版, 2017 Error distance plays an important role in the decoding of standard Reed-Solomon codes. In 2012, Hong and Wu proposed a famous conjecture of standard Reed-Solomon codes on error distance.
SONG Qing-Shan +2 more
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Bootstrap for estimating the mean squared error of the spatial EBLUP [PDF]
, 2007 This work assumes that the small area quantities of interest follow a Fay-Herriot model with spatially correlated random area effects. Under this model, parametric and nonparametric bootstrap procedures are proposed for estimating the mean squared ...
MOLINA ISABEL +6 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Standard Error of the Mean and Minimal Detectable Change of Gait Speed in Older Adults Using Japanese Long-Term Care Insurance System. [PDF]
Gerontol Geriatr Med, 2021 Takada Y, Tanaka S.
europepmc +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Mechanisms of Error Development in Inertial Navigation Systems [PDF]
The processes of error development in an inertial navigation system are analysed. With this aim, the standard structures of error development were extracted in the inertial system. Error development was defined in the standard structures.
Šestakovs, Vladimirs +3 more
core
Unequal Error Protection Irregular Over-Complete Mapping for Wavelet Coded Wireless Video Telephony Using Iterative Source and Channel Decoding [PDF]
, 2008 —Since the different bits of the compressed video sequence produced by the BBC’s wavelet-based video codec exhibit different error sensitivity, efficient Unequal Error Protection (UEP) schemes have to be used to ensure that the perceptually more ...
Pham Quang, A, Yang, L-L, Hanzo, L.
core