A multi-institutional EPID-based 3D dose reconstruction model in a virtual phantom for standardized patient QA, benchmarking and auditing for stereotactic radiosurgery. [PDF]
Zwan B +19 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
The Digital Standardized Patient: An Artificial Intelligence Coach for Cultural Dexterity in Surgical Care. [PDF]
Rao AS +9 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Enhancing gastric ultrasound training with standardized patient-based drinking simulation: a self-controlled study. [PDF]
Ke M, Wei T, He Z, Lu W, Xie X.
europepmc +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Dental Students' Perceptions of Standardized Patient Experiences Conducted Virtually: A Multi-Year Qualitative Study. [PDF]
Desai JP, McQuistan MR, Young LB.
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Code Status Discussions: A Standardized Patient Workshop for Senior Medical Students. [PDF]
Bechtold H +7 more
europepmc +1 more source

