Results 81 to 90 of about 1,237,785 (303)

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Attention training through gaze-contingent feedback: effects on reappraisal and negative emotions [PDF]

open access: yes, 2016
Reappraisal is central to emotion regulation but its mechanisms are unclear. This study tested the theoretical prediction that emotional attention bias is linked to reappraisal of negative emotion-eliciting stimuli and subsequent emotional responding ...
Everaert, Jonas   +2 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical Diagnosis and Treatment of 31 Children with Mycoplasma pneumoniae Necrotizing Pneumonia

open access: yesInternational Journal of General Medicine
Zhaoxia Wang,1 Yuxin Zhao,2 Hongfang Liu3 1Department of Pediatrics, Weihai Central Hospital Affiliated to Qingdao University, Weihai, Shandong, People’s Republic of China; 2Department of Ophthalmology, Weihai Central Hospital Affiliated to Qingdao ...
Wang Z, Zhao Y, Liu H
doaj  

Cross-domain Semantic Parsing via Paraphrasing

open access: yes, 2017
Existing studies on semantic parsing mainly focus on the in-domain setting. We formulate cross-domain semantic parsing as a domain adaptation problem: train a semantic parser on some source domains and then adapt it to the target domain.
Su, Yu, Yan, Xifeng
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Needs Assessment of Suicide Prevention in Vermont Middle and High Schools [PDF]

open access: yes, 2018
Introduction. Adolescent suicide is epidemic. 17% of high school students con- sidered suicide and 8% attempting to take their lives in 2015 nationwide.
Chawla, Rajan   +9 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Does the Quality of Training Programs Matter? Evidence from Bidding Processes Data [PDF]

open access: yes
This paper estimates the effect of training quality on labor-market earnings using a Peruvian non-experimental training program, PROJOVEN, which targets disadvantaged youths aged 16 to 24 years. The identification of causal effects is possible because of
Alberto Chong, José Galdo
core  

Implementing Observation Protocols: Lessons for K-12 Education From the Field of Early Childhood [PDF]

open access: yes, 2012
Examines issues for implementing standardized observation protocols for teacher evaluations. Makes recommendations based on lessons from preschool, such as the need to show empirical links between teacher performance and student learning and ...
Robert C. Pianta
core  

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