Results 51 to 60 of about 244,591 (283)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Gallia Préhistoire, 2018 The site of Kercado, in Carnac, is situated above the valley of Kerloquet and the ria that runs along the beach of Kerdual for 2 km. It comprises a probable low mound, the cairn of Mané er Groez, with a passage grave, and a curvilinear enclosure of about
Serge Cassen +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
The engraved monoliths in the Mané er Groez Neolithic passage tomb in Kercado (Carnac, Morbihan)
Gallia Préhistoire, 2018 The site of Kercado, in Carnac, is situated above the valley of Kerloquet and the ria that runs along the beach of Kerdual for 2 km. It comprises a probable low mound, the cairn of Mané er Groez, with a passage grave, and a curvilinear enclosure of about
Serge Cassen +2 more
doaj +1 more source
Daniel Mowry Cemetery Condition Reports [PDF]
, 2018 This cemetery contains 85 burials. Transcriptions here include all of the markings on each stone located within the cemetery. Additionally, if stones were illegible a rubbing of the stone was completed.
Beeson, Nick +9 more
core +1 more source
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Circumstances contributing to the deterioration of old cob structures in Japan
Journal of Asian Architecture and Building Engineering, 2022 The benefits of using earthen material such as cob in architecture are increasingly acknowledged, yet remaining concerns about safety prevent its broader use. This is particularly true in areas that experience earthquakes and heavy rain.
Emily K. Reynolds, Muramoto Makoto
doaj +1 more source
The Soft Side of Stone: Notes for a Phenomenology of Stone [PDF]
, 2007 Stone represents the firmness and intransigence of the world within which we live and act. But beyond the perception and appropriations of stone, diverse meanings lie hidden between the hardness of stone and its uses.
Berleant, Arnold
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Medicine Science, 2020 Cholecystectomy is one of the most common types of surgical operations and includes many pathologies ranging from the most common cholecysistitis to randomly detected dysplasia and cancer. In this study, it is aimed to obtain a general regional incidence
Sirin Kucuk +4 more
doaj +1 more source