Results 71 to 80 of about 2,139,311 (253)

Effects of Inbreeding and Environmental Factors on Fleece Characteristics in Markhoz Goats

Journal of Natural Fibers
The Markhoz goat is an endangered Iranian mohair-producing breed, raising concerns about genetic diversity and inbreeding depression. This study examined the effects of inbreeding and key environmental factors (sex, age, coat color) on fleece traits in ...
Parinaz Karimi, Amir Rashidi, Mohammad Razmkabir, Peyman Mahmoudi   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Comparative effectiveness of nitinol staple-only fixation versus antiglide plate fixation for Weber type B distal fibular fractures

BMC Musculoskeletal Disorders
Background Interest in less invasive surgeries for Weber type B distal fibular fracture has increased recently. This study aimed to demonstrate that nitinol staple-only fixation is less invasive compared to antiglide plate fixation. Materials and methods
Kensei Yoshimoto, Masahiko Noguchi, Takumi Koseki, Ayako Tominaga, Ken Okazaki   +4 more
doaj   +1 more source

Primary Repair for Injury of Medial Collateral Ligament During Total Knee Arthroplasty

Orthopaedic Journal of Sports Medicine, 2020
This study, we aim to determine whether intraoperative over-release of MCL that is treated with primary repair can achieve satisfactory clinical results when compared to those who did not have over-release of MCL.
Cheng Jin MD, PhD, Jia-yi Zhao MD, Jong-Keun Seon MD, PhD, Asep Santoso   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Staple food prices in Mozambique [PDF]

Prepared for the Comesa policy seminar on “Variation in staple food prices: Causes, consequence, and policy options”, Maputo, Mozambique, 25-26 January 2010 under the Comesa-MSU-IFPRI African Agricultural Marketing Project (AAMP)Mozambique, food security,
Tostao, Emilio, Donovan, Cynthia
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Fiber length and its phenotypic role in fleece coverage and genotype-based biotype identification in South American domestic camelids

Open Veterinary Journal
Background: Accurate biotype identification in South American domestic camelids (SAC) reared in mixed herds remains a persistent challenge. Phenotypic classifications have been limited by outdated information and an over-reliance on morphological traits,
Alfonso Flores-Gutiérrez, Alejandro Prieto, Melina Castillo, María Flavia Castillo, Eduardo Narciso Frank   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The influence of staple strength, length, curvature and diameter distribution on price and processing performance

, 2005
The influence of staple strength, length, curvature and diameter distribution on price and processing ...
Peter Lamb (13089453), K Curtis (13322022)   +1 more
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