Results 81 to 90 of about 429,563 (275)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Dynamics of Star Cluster Formation: The Effects of Ongoing Star Formation and Stellar Feedback

The Astrophysical Journal
We perform a high-resolution zoomed-in simulation of star cluster assembly including the merger of two subclusters with initial conditions taken from previous large-scale giant molecular cloud (GMC) simulations.
Jeremy Karam, Michiko S. Fujii, Alison Sills   +2 more
doaj   +1 more source

Star Clusters in the Nearby Late-Type Galaxy NGC 1311

, 2007
Ultraviolet, optical and near infrared images of the nearby (D ~ 5.5 Mpc) SBm galaxy NGC 1311, obtained with the Hubble Space Telescope, reveal a small population of 13 candidate star clusters.
Ashman K. M. & Zepf S. E., Baade W., Binney J. & Merrifield M., Corbin M. R., de Jong R. S., de Vaucouleurs G., Koo D. C. & Kron R. G., Noll K., Paul B. Eskridge, Peter Anders, Richard de Grijs, Rogier A. Windhorst, Rolf A. Jansen, Stover R. J., Violet A. Mager   +14 more
core   +1 more source

VERTICO IV: Environmental Effects on the Gas Distribution and Star Formation Efficiency of Virgo Cluster Spirals [PDF]

, 2022
Vicente Villanueva, Alberto D. Bolatto, S. N. Vogel, Toby Brown, C. D. Wilson, Nikki Zabel, Sara L. Ellison, Adam R. H. Stevens, Maria Jesus Jimenez Donaire, Kristine Spekkens, Mallory Thorp, Timothy A. Davis, Laura C. Parker, Ian Roberts, Dhruv Bisaria, A. Boselli, Barbara Catinella, Aeree Chung, L. Cortese, Bumhyun Lee, Adam C. Watts   +20 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Deep Galaxy Stellar Mass Functions As a Function of Star Formation Rate in the Virgo Cluster Environment

The Astrophysical Journal
We analyze deep ( M _* ≳ 10 ^7 M _⊙ ) galaxy stellar mass functions (SMFs) of the Virgo cluster using stellar masses derived as part of the Next Generation Virgo Survey. The total SMF has a slope of $\alpha =-1.3{5}_{-0.02}^{+0.02}$ , which is similar to
Cameron R. Morgan, Elizaveta Sazonova, Ian D. Roberts, Michael L. Balogh, Joel Roediger, Laura Ferrarese, Patrick Côté, Alessandro Boselli, Matteo Fossati, Jean-Charles Cuillandre, Stephen Gwyn   +10 more
doaj   +1 more source

Nitrogen-enriched, Highly Pressurized Nebular Clouds Surrounding a Super Star Cluster at Cosmic Noon

The Astrophysical Journal, 2023
Strong lensing offers a precious opportunity for studying the formation and early evolution of super star clusters that are rare in our cosmic backyard.
Massimo Pascale, Liang Dai, Christopher F. McKee, Benny T.-H. Tsang   +3 more
doaj   +1 more source

The star cluster mass--galactocentric radius relation: Implications for cluster formation

, 2015
Whether or not the initial star cluster mass function is established through a universal, galactocentric-distance-independent stochastic process, on the scales of individual galaxies, remains an unsolved problem.
Cameron, Ewan, de Grijs, Richard, Fan, Zhou, Sun, Weijia   +3 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Probing Obscured Star Formation in Galaxy Clusters Using JWST Medium-band Images: 3.3 μm PAH Emitter Sample in A2744

The Astrophysical Journal Supplement Series
Star-forming galaxies in galaxy clusters play a crucial role in understanding the advanced stages of galaxy evolution within dense environments. We present a sample of 3.3 μ m polycyclic aromatic hydrocarbon (PAH)-bright galaxies in the A2744 galaxy ...
Cheng Cheng, Xin Wang, Piaoran Liang, Fengwu Sun, Edo Ibar, Malte Brinch, Haojing Yan, Jia-Sheng Huang, Jun Li, Juan Molina   +9 more
doaj   +1 more source