Results 51 to 60 of about 79,269 (269)
Rotation and Hα Emission in a Young SMC Cluster: A Spectroscopic View of NGC 330
The Astrophysical JournalWe present an analysis of high-resolution optical spectra recorded for 30 stars of the split extended main-sequence turnoff of the young (∼40 Myr) Small Magellanic Cloud globular cluster NGC 330.
Paul I. Cristofari +6 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Velocity Dispersion Profile of Nine Open Clusters in the Solar Neighborhood
The Astrophysical JournalWe analyze the velocity dispersion profiles of nine open clusters in the solar neighborhood using kinematic data from Gaia DR 3, aiming to identify potential dynamical signatures of stellar-mass black holes through a comparison of theoretical and ...
Bingqian Ma +4 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Massive Star Cluster Formation with Binaries. I. Evolution of Binary Populations
The Astrophysical JournalWe study the evolution of populations of binary stars within massive cluster-forming regions. We simulate the formation of young massive star clusters within giant molecular clouds with masses ranging from 2 × 10 ^4 to 3.2 × 10 ^5 M _⊙ .
Claude Cournoyer-Cloutier +9 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Semiempirical versus Theoretical Stellar Population Models: A Comparison with Star Clusters
The Astronomical JournalStellar population synthesis (SPS) models are a key tool for deriving the age, metallicity, radial velocity, and reddening of star clusters from their integrated spectra.
Randa Asa’d +5 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Astronomical JournalWe present the results from spectroscopic and photometric analysis of 17 globular cluster (GC) candidates in the Irr II galaxy NGC 3077. The GC candidates were selected on the Hubble Space Telescope images and were cleaned of foreground Galatic stars ...
P. A. Ovando +6 more
doaj +1 more source