Results 151 to 160 of about 202,775 (306)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Fast and inefficient star formation due to short-lived molecular clouds and rapid feedback. [PDF]

Nature, 2019
Kruijssen JMD, Schruba A, Chevance M, Longmore SN, Hygate APS, Haydon DT, McLeod AF, Dalcanton JJ, Tacconi LJ, van Dishoeck EF.   +9 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

STAR FORMATION AT <i>Z</i> = 2.481 IN THE LENSED GALAXY SDSS J1110+6459: STAR FORMATION DOWN TO 30 PARSEC SCALES. [PDF]

Astrophys J Lett, 2017
Johnson TL, Rigby JR, Sharon K, Gladders MD, Florian M, Bayliss MB, Wuyts E, Whitaker KE, Livermore R, Murray KT.   +9 more
europepmc   +1 more source

The Evolution of the Star Formation of zCOSMOS and SDSS galaxies at z<0.7 as a Function of Mass and Structural Parameters [PDF]

, 2009
C. Maier, S. J. Lilly, G. Zamorani, M. Scodeggio, F. Lamareille, T. Contini, M. Sargent, Claudia Scarlata, Pascal A. Oesch, C. M. Carollo, Zcosmos Team   +10 more
openalex  

HOPS 108: Star-formation triggered by a non-thermal jet? [PDF]

, 2017
Ana Karla Díaz-Rodríguez, Mayra Osorio, Guillem Anglada, S. T. Megeath, L. F. Rodríguez, John Tobin, Elise Furlan, José F. Gómez, Amelia M. Stutz, Will Fischer, P. Manoj, B. M. González-García, Thomas Stanke, Joseph Booker, B. Ali   +14 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

GALAXY STRUCTURE, STELLAR POPULATIONS, AND STAR FORMATION QUENCHING AT 0.6 ≲ <i>z</i> ≲ 1.2. [PDF]

Astrophys J, 2018
Kim K, Malhotra S, Rhoads JE, Joshi B, Fererras I, Pasquali A.   +5 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Triggered Star Formation inside the Shell of a Wolf-Rayet Bubble as the Origin of the Solar System. [PDF]

Proc Int Astron Union, 2018
Dwarkadas VV, Dauphas N, Meyer B, Boyajian P, Bojazi M.   +4 more
europepmc   +1 more source